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Postion:Product Catalog >ABT-963
ABT-963
  • ABT-963

ABT-963 NEW

Price $293 $722 $987
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-20

Product Details

Product Name: ABT-963 CAS No.: 266320-83-6
Purity: 99.85% Supply Ability: 10g
Release date: 2024/11/20

Product Introduction

Bioactivity

NameABT-963
DescriptionABT-963 is a potent and selective inhibitor of disubstituted pyridazinone cyclooxygenase-2 (LOX2) that dose-dependently reduces injury perception in a carrageenan model of nociceptive sensitization.ABT-963 is used in the study of arthritis.
In vivoFollowing oral administration, ABT-963 decreased prostaglandin E2 production in a rat carrageenan airbag model (ED50 of 0.4 mg/kg) and reduced edema in a carrageenan-induced paw edema model with an ED30 of 1.9 mg/kg.ABT-963 dose-dependently decreased injury perception in a carrageenan nociceptive hypersensitivity model (ED50 of 3.1 mg/kg ). After 14 days of administration in an adjuvant arthritis model, ABT-963 had an ED(50) of 1.0 mg/kg in reducing hind paw swelling.[1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
KeywordsABT-963
Inhibitors Related2,5-Di-tert-butylhydroquinone | Caffeic Acid | 5-LOX inhibitor | Diethylcarbamazine citrate | Phenidone | Resveratrol | NNK | PF-4191834 | 5-Aminosalicylic Acid | Malotilate
Related Compound LibrariesBioactive Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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