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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antiviral drugs> Raltegravir
 Raltegravir
  •  Raltegravir
  •  Raltegravir
  •  Raltegravir
  •  Raltegravir
  •  Raltegravir

Raltegravir

Price $1
Package 1T
Min. Order: 1T
Supply Ability: 20tons
Update Time: 2024-10-25

Product Details

Product Name: Raltegravir CAS No.: 518048-05-0
EC-No.: 610-733-3 Min. Order: 1T
Purity: 99% Supply Ability: 20tons
Release date: 2024/10/25

Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN. Raltegravir, also known as MK-0518, is an antiretroviral drug used to treat HIV infection. Raltegravir is a human immunodeficiency virus (HIV) integrase strand transfer inhibitor (HIV-1 INSTI) with HIV-1 antiviral activity. Raltegravir binds to and inhibits integrase, an HIV enzyme that inserts viral genetic material into the genetic material of the infected human cell. Inhibition of integrase prevents insertion of HIV DNA into the human DNA genome, thus blocking HIV replication. It received approval by the U.S. Food and Drug Administration (FDA) in October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.

Application

Raltegravir ,It can be combined with other antiretroviral drugs for the treatment of human immunodeficiency virus (HIV) -1 infection. It slows down HIV-1 infection by inhibiting the HIV integrase required for viral replication. When Rett Kawet with other anti HIV drugs can reduce the number of HIV in blood, and the increase of CD4+T cells known as the number of white blood cells, contribute to the anti infection. Show with Lito Bernard Vee, efavirenz, tenofovir for Ranave, the interaction of the goods and drug resistance no cross resistance and has a synergistic effect with multiple drugs.

Raltegravir (RAL), , used to treat HIV infection.

In a study of the drug as part of combination therapy, raltegravir exhibited potent and durable antiretroviral activity similar to that of efavirenz at 24 and 48 weeks but achieved HIV-1 RNA levels below detection at a more rapid rate. After 24 and 48 weeks of treatment, raltegravir did not result in increased serum levels of total cholesterol, low-density lipoprotein cholesterol, or triglycerides

Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN.

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Company Profile Introduction

Hebei Yanxi Chemical Co. LTD., mainly produce the Carbomer940/980/u21 and lead acetate and lead oxide, lead stearate, lead salt, at the same time operating organic intermediates, surfactants, Food additive,inorganic salt, plant extracts, cosmetics raw material, etc., through long-term development, hebei said bush chemical co., LTD. In hebei province has become a collection of r &d, production, sales in the integration of high-tech enterprises.

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  • Since: 2020-05-25
  • Address: Zhanggeji Village, Fengjiazhai Town, Guangzong County, Xingtai City, Hebei Province
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