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Postion:Product Catalog >Chemical Reagents>Organic reagents>Tricyclic compound>9-Phenanthrol
9-Phenanthrol
  • 9-Phenanthrol

9-Phenanthrol NEW

Price $41 $53 $76
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: 9-Phenanthrol CAS No.: 484-17-3
Purity: 98.72% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Name9-Phenanthrol
Description9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.
In vitroIn addition, 9-phenanthrol, lacking the chemical groups necessary for CFTR activation, also reversibly inhibited TRPM4 with a similar IC(50). Channel inhibition was voltage independent. The IC(50) determined in the whole-cell and inside-out experiments were similar, suggesting a direct effect of the molecule. However, 9-phenanthrol was ineffective on TRPM5, the most closely related channel within the TRP protein family. We identify 9-phenanthrol as a TRPM4 inhibitor, without effects on TRPM5. It could be valuable in investigating the physiological functions of TRPM4, as distinct from those of TRPM5[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 19 mg/mL (97.82 mM), Sonication is recommended.
Ethanol : 9 mg/mL (46.34 mM), Sonication is recommended.
Keywordsischemia-reperfusion injury | inhibit | TRPM4 | NSC-50554 | 9Phenanthrol | Inhibitor | NSC 50554 | TRP Channel | 9-Hydroxyphenanthrene | Transient receptor potential channels | 9 Phenanthrol | NSC50554 | 9-Phenanthrol
Inhibitors Related(+)-Camphor | Camphor | 1,4-Cineole
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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