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Postion:Product Catalog >Chemical Reagents>Organic reagents>Esters>Lactones>DL-Mevalonolactone
DL-Mevalonolactone
  • DL-Mevalonolactone
  • DL-Mevalonolactone
  • DL-Mevalonolactone
  • DL-Mevalonolactone
  • DL-Mevalonolactone

DL-Mevalonolactone

Price $8
Package 1KG
Min. Order: 1g
Supply Ability: kg--tons
Update Time: 2020-03-06

Product Details

Product Name: DL-Mevalonolactone CAS No.: 674-26-0
Min. Order: 1g Purity: ≥98%
Supply Ability: kg--tons Release date: 2020/03/06
Storage:: Keep away from heat, sparks and flames Package:: Bottle / Drum / Bag
Delivery Time:: Prompt Transportation:: By sea, express, air
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[Product Specification]

 

 Names

Name
DL-Mevalonolactone
Synonym
More Synonyms

 DL-Mevalonolactone Biological Activity

Description
DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (?Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].
Related Catalog
Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease
References

[1]. Domingos SR, et al. On the structural intricacies of a metabolic precursor: Direct spectroscopic detection of water-induced conformational reshaping of mevalonolactone. J Chem Phys. 2017 Sep 28;147(12):124310.

[2]. Cecatto C, et al. Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria. Neurochem Int. 2017 Sep;108:133-145.

 Chemical & Physical Properties

Density
1.189 g/cm3
Boiling Point
145-150 °C5 mm Hg(lit.)
Melting Point
28 °C(lit.)
Molecular Formula
C6H10O3
Molecular Weight
130.14200
Flash Point
>230 °F
Exact Mass
130.06300
PSA
46.53000
LogP
0.07440
Index of Refraction
n20/D 1.473(lit.)
Storage condition
2-8°C
Stability
Hygroscopic

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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