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Postion:Product Catalog >Biochemical Engineering>Polypeptide> ALX 0600
	ALX 0600
  • 	ALX 0600

ALX 0600

Price $7
Package 1KG
Min. Order: 1KG
Supply Ability: 100KG
Update Time: 2020-02-14

Product Details

Product Name: ALX 0600 CAS No.: 197922-42-2
Min. Order: 1KG Purity: 99%
Supply Ability: 100KG Release date: 2020/02/14
Name: Judy Liang 607
Product Name: ALX 0600
Synonyms: ALX 0600;Gattex;Glucagon-like peptide II [2-glycine] (human);Teduglutide
CAS: 197922-42-2
MF: C164H252N44O55S
MW: 3752.08248
EINECS:
Product Categories:
Mol File: 197922-42-2.mol
ALX 0600 Structure
ALX 0600 Chemical Properties
Safety Information
MSDS Information
ALX 0600 Usage And Synthesis
Description Teduglutide was approved in August 2012 by the European Commission and in December 2012 by the US FDA for the treatment of adults with short bowel syndrome (SBS) who are dependent on parenteral nutrition (PN). Teduglutide (also known as ALX-0600) is a GLP-2 analogue in which glycine has been substituted for alanine at position 2 from the N-terminus, thereby conferring resistance to degradation by DPP-4. Teduglutide has similar binding affinity, agonist potency, and agonist efficacy as GLP-2 in assays with the rat GLP-2 receptor. Administration of teduglutide to rats gave a significant increase in small intestine weight and an increase in the height of intestinal villi. Teduglutide was prepared by solid-phase peptide synthesis.
Originator NPS Allelix (Canada)
Uses Treatment of intestinal diseases characterized by chemical or surgical damage of the intestinal epithelium such as Short Bowel Syndrome (SBS) or damage to the intestinal epithelium due to disease (glucagon-like peptide-2 (GLP- 2) analog).
Definition ChEBI: A 33-membered polypeptide consisting of His, Gly, Asp, Gly, Ser, Phe, Ser, Asp, Glu, Met, Asn, Thr, Ile, Leu, Asp, Asn, Leu, Ala, Ala, Arg, Asp, Phe, Ile, Asn, Trp, Leu, Ile, Gln, Thr, Lys, Ile, Thr and Asp residues joined in sequence. A glucagon-like pep ide-2 receptor agonist used for the treatment of short-bowel syndrome.
Brand name Gattex

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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