Pioglitazone
Price | $7 |
Package | 1KG |
Min. Order: | 1KG |
Supply Ability: | 100KG |
Update Time: | 2020-02-13 |
Product Details
Product Name: Pioglitazone | CAS No.: 111025-46-8 |
Min. Order: 1KG | Purity: 99% |
Supply Ability: 100KG | Release date: 2020/02/13 |
Name : Judy Liang 607 |
Product Name: Pioglitazone
Synonyms: 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl]thiazolidine-2,4-dione;Pioglitazone (Actos);2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]Methyl]-;Pioglitazone 5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;5-[4-[2-(5-ETHYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL-2,4-THIAZOLIDINEDIONE;5-(4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE;Pioglitazone;PIOGLITAZONE HCL(5-[[4-[2-(5-ETHYLPYRIDIN-2-YL)ETHOXY]PHENYL]METHYL]THIAZOLIDINE-2,4-DIONE, HCL)
CAS: 111025-46-8
MF: C19H20N2O3S
MW: 356.44
EINECS: 601-029-7
Product Categories: APIS;LESCOL
Mol File: 111025-46-8.mol
Pioglitazone Structure
Pioglitazone Chemical Properties
Melting point 183-184 C
Boiling point 575.4±45.0 °C(Predicted)
density 1.260±0.06 g/cm3(Predicted)
form White to off-white solid.
pka 6.35±0.50(Predicted)
Safety Information
Hazard Codes F,C
Risk Statements 11-34
Safety Statements 16-26-36/37/39-45
Hazardous Substances Data 111025-46-8(Hazardous Substances Data)
MSDS Information
Provider Language
Pioglitazone English
Pioglitazone Usage And Synthesis
Uses antihyperlipidemic, HMGCoA reductase inhibitor
Definition ChEBI: A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic acti ity.
Indications Pioglitazone is approved for use as monotherapy and in conjunction with metformin, sulfonylureas, and insulin. It is taken once a day with or without food. Though pioglitazone may also cause a small increase in low-density lipoprotein concentrations, there is usually a modest decrease in triglyceride levels, but it unclear whether this has any clinical significance or persists in the long term.
Brand name Actos (Takeda).
General Description Pioglitazone, (±)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione (Actos),is an odorless, white, crystalline powder that must be convertedto a salt such as its hydrochloride before it will haveany water solubility. Although the molecule contains one chiralcenter, the compound is used as the racemic mixture. Thisis primarily a result of the in vivo interconversion of the twoenantiomers. Thus, there are no differences in the pharmacologicalactivity of the two enantiomers.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
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- Since: 2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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