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Postion:Product Catalog >3'-Demethylnobiletin
3'-Demethylnobiletin
  • 3'-Demethylnobiletin
  • 3'-Demethylnobiletin
  • 3'-Demethylnobiletin
  • 3'-Demethylnobiletin
  • 3'-Demethylnobiletin

3'-Demethylnobiletin

Price $9.8
Package 1KG
Min. Order: 1KG
Supply Ability: 20 tons
Update Time: 2020-02-07

Product Details

Product Name: 3'-Demethylnobiletin CAS No.: 112448-39-2
Min. Order: 1KG Purity: >98%HPLC
Supply Ability: 20 tons Release date: 2020/02/07
Delivery Time:: Prompt Storage:: Keep away from heat, sparks and flames
Package:: Bottle / Drum / Bag Port:: Shanghai, Tianjin or Qingdao
Transportation:: By sea, express, air,railway No. :: Jessie

Jessie 785

Contact: jessie@coreychem.com

Welcome to contact us!

 

[Product Specification】

Names

Name
2-(3-hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one
Synonym
More Synonyms

 3'-Demethylnobiletin Biological Activity

Description
3'-Demethylnobiletin, a derivative of Nobiletin, is a polymethoxyflavonoid in citrus fruits[1]. Nobiletin exhibits anticancer activity and inhibits tumor angiogenesis by regulating Src, FAK, and STAT3 signaling[2].
Related Catalog
Research Areas >> Cancer
Signaling Pathways >> Others >> Others
References

[1]. Murakami A, et al. In vitro absorption and metabolism of nobiletin, a chemopreventive polymethoxyflavonoid in citrus fruits. Biosci Biotechnol Biochem. 2001 Jan;65(1):194-7.

[2]. Sp N, et al. Nobiletin Inhibits Angiogenesis by Regulating Src/FAK/STAT3-Mediated Signaling through PXN in ER+ Breast Cancer Cells. Int J Mol Sci. 2017 Apr 30;18(5). pii: E935.

 Chemical & Physical Properties

Density
1.304g/cm3
Boiling Point
613.8ºC at 760 mmHg
Melting Point
170-171 ºC
Molecular Formula
C20H20O8
Molecular Weight
388.36800
Flash Point
218.8ºC
Exact Mass
388.11600
PSA
96.59000
LogP
3.20860
Vapour Pressure
1.17E-15mmHg at 25°C
Index of Refraction
1.582
Water Solubility
Practically insoluble (0.039 g/L) (25 ºC)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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