Spirapril hydrochloride
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 100kg |
| Update Time: | 2020-01-15 |
Product Details
| Product Name: Spirapril hydrochloride | CAS No.: 94841-17-5 |
| Min. Order: 1KG | Purity: 99.0% |
| Supply Ability: 100kg | Release date: 2020/01/15 |
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Spirapril hydrochloride Basic information
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Product Name:
Spirapril hydrochloride
Synonyms:
Renormax;Renpress;Sandopril;TI 211-950;1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid, 7-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, monohydrochloride, (8S-(7(R*(R*)),8R*))-;Spirapril HCl;Unii-occ25lm897;Spirapril hydrochloride
CAS:
94841-17-5
MF:
C22H30N2O5S2.HCl
MW:
503.07
EINECS:
Product Categories:
Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API
Mol File:
94841-17-5.mol
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Spirapril hydrochloride Chemical Properties
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Melting point
192-1940C (dec.)
alpha
D26 -11.2° (c = 0.4 in ethanol)
storage temp.
-20°C Freezer
solubility
Very slightly soluble in water, soluble in methanol, slightly soluble in acetonitrile, practically insoluble in methylene chloride.
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Safety Information
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MSDS Information
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Spirapril hydrochloride Usage And Synthesis
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Description
Spirapril hydrochloride is a new ACE inhibitor introduced in Finland for the treatment of hypertension. Spirapril is orally active and rapidly absorbed and converted to the active diacid spiraprilat which produces a reduction in blood pressure similar to that seen with enalapril and captopril. Spirapril has been reported to be well tolerated and exhibits an apparently lower incidence of cough compared with other ACE inhibitors. The elimination of spirapril occurs via both renal and hepatic routes so that no dosage adjustment is required for patients with renal impairment. In patients with severe congestive heart failure, spirapril has demonstrated beneficial hemodynamic effects with a duration of action >24 hours.
Chemical Properties
White Solid
Originator
Schering-Plough (U.S.A.)
Uses
Angiotensin-converting enzyme (ACE) inhibior. Antihypertensive
Brand name
Renormax (Schering);Renpress.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
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