Novobiocin
| Price | $1 |
| Package | 1g |
| Min. Order: | 1g |
| Supply Ability: | g/kg/Ton |
| Update Time: | 2019-12-26 |
Product Details
| Product Name: Novobiocin | CAS No.: 303-81-1 |
| EC-No.: 206-146-3 | Min. Order: 1g |
| Purity: ≥98% | Supply Ability: g/kg/Ton |
| Release date: 2019/12/26 | |
| Transportation: By air/Bay Sea/Express | Packaging: Bottle/Durm/Bag |
| Delivery Time: Prompt |
Heidi 0712
Email:heidi@coreychem.com
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Novobiocin Basic information
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Product Name:
Novobiocin
Synonyms:
NOVOBIOCIN;cathocin;cathomycin;crystallinicacid;-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2h-1-benzopyran-3-yl)-4-hydroxy-;inamycin;novo-r;pa93
CAS:
303-81-1
MF:
C31H36N2O11
MW:
612.628
EINECS:
206-146-3
Product Categories:
Mol File:
303-81-1.mol
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Novobiocin Chemical Properties
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Melting point
170-172 °C
alpha
D24 -63.0° (c = 1 in ethanol)
Boiling point
657.29°C (rough estimate)
density
1.3448
refractive index
1.5800 (estimate)
pka
pKa1 4.3; pKa2 9.1(at 25℃)
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Safety Information
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WGK Germany
3
HS Code
2941906000
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MSDS Information
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Novobiocin Usage And Synthesis
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Chemical Properties
A light-yellow to white antibiotic produced by Streptomyces niveus. Available as calcium and sodium salts.
Uses
Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram positive activity and was used clinically. Novobiocin is a potent inhibitor of bacterial DNA gyrase and a competitive inhibitor of the ATPase reaction catalysed by GyrB.
Uses
Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram positive antibiotic activity and was used clinically. Novobiocin is a potent inhibitor of bacterial DNA gyrase and a competitive inhibitor of the ATPase reaction catalysed by GyrB.
Definition
ChEBI: A coumarin-derived antibiotic obtained from Streptomyces niveus.
Brand name
Albamycin.
World Health Organization (WHO)
Novobiocin, an antibiotic with a narrow spectrum of activity, was introduced in 1956. Its use was subsequently associated with serious adverse effects including blood dyscrasias. In view of its toxicity there are no current valid indications for its use. Although preparations containing novobiocin may remain available in some countries it has largely lapsed into disuse.
Hazard
May have damaging side effects.
Veterinary Drugs and Treatments
Novobiocin is approved as a single agent and in combination with penicillin G for use in dry dairy cattle as a mastitis tube. Novobiocin is available in combination with tetracycline and prednisolone for oral use in dogs.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
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