IWR-1-endo
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 100kgs |
| Update Time: | 2019-12-20 |
Product Details
| Product Name: IWR-1-endo | CAS No.: 1127442-82-3 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: 100kgs | Release date: 2019/12/20 |
Mary 0003
▼
▲
Product Name:
IWR-1-endo
Synonyms:
rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide IWR-1-endo;IWR-1-endo, >=98%;IWR-1(IWR-1-endo);4-(1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl)-N-8-quinolinyl-Benzamide (IWR-1);[(3aR*,4S*,7R*,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide;endo-IWR 1;IWR-1-endo - IWR-1 | endo-IWR-1;IWR-1
CAS:
1127442-82-3
MF:
C25H19N3O3
MW:
409
EINECS:
Product Categories:
Inhibitors;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:
1127442-82-3.mol
▼
▲
IWR-1-endo Chemical Properties
▼
▲
alpha
-3.0～+3.0°(20℃/D)(c=0.1,CH3CN)
Boiling point
643.9±55.0 °C(Predicted)
density
1.425±0.06 g/cm3(Predicted)
storage temp.
Store at RT
solubility
DMSO: soluble5mg/mL, clear
form
Liquid
pka
11.88±0.43(Predicted)
color
white to beige
▼
▲
Safety Information
▼
▲
WGK Germany
3
▼
▲
MSDS Information
▼
▲
IWR-1-endo Usage And Synthesis
▼
▲
Uses
IWR-1-endo act as inhibitors of Wnt response. It appear that IWR compounds induce stabilization of Axin proteins via a direct interaction, which is a part of the b-catenin destruction complex (consists of Apc, Axin, Ck1 and Gsk3b). Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosi s.
▼
▲
IWR-1-endo Preparation Products And Raw materials
▼
▲
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $50.00/5mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
| $10.00/1KG |
VIP6Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-11-21 | |
| $0.00/500g |
VIP4Y
|
Henan Research New Materials Co., Ltd.
|
2024-11-20 | |
| $29.00/5mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 |
China- Since: 2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
INQUIRY