ROSCOVITINE
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 20kg |
| Update Time: | 2019-09-06 |
Product Details
| Product Name: ROSCOVITINE | CAS No.: 186692-46-6 |
| Min. Order: 1KG | Purity: 98% |
| Supply Ability: 20kg | Release date: 2019/09/06 |
Abby043
▼
▲
▼
▲
▼
▲
▼
▲
▼
▲
▼
▲
▼
▲
ROSCOVITINE Basic information
▼
▲
Product Name:
ROSCOVITINE
Synonyms:
Roscovitine - CAS 186692-46-6 - Calbiochem;2-(R)-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE;2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE;6-BENZYLAMINO-2-(R)-[(1-ETHYL)-2-HYDROXYETHYLAMINO]-9-ISOPROPYLPURINE;ROSCOVITINE;(R)-ROSCOVITINE;(R)-2-(1-ETHYL-2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-ISOPROPYLPURINE;P34 CDC2
CAS:
186692-46-6
MF:
C19H26N6O
MW:
354.45
EINECS:
Product Categories:
-;API intermediates;Apis;Inhibitors
Mol File:
186692-46-6.mol
▼
▲
ROSCOVITINE Chemical Properties
▼
▲
Melting point
106～107℃
density
1.3
storage temp.
−20°C
form
White to off-white solid
InChIKey
BTIHMVBBUGXLCJ-OAHLLOKOSA-N
CAS DataBase Reference
186692-46-6(CAS DataBase Reference)
▼
▲
Safety Information
▼
▲
Safety Statements
22-24/25
WGK Germany
3
HS Code
29335990
▼
▲
MSDS Information
▼
▲
SigmaAldrich
English
▼
▲
ROSCOVITINE Usage And Synthesis
▼
▲
Uses
Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). Roscovitine has been found to produce apoptosis in treated cancerous cells of non-small cell lung cancer (NSCLC) and other cancers. Studies show that Roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle. Roscovitine maybe useful in the treatment of non-small cell lung c ancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.
Definition
ChEBI: 2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors.
Anticancer Research
Roscovitine a derivative of olomoucine which is isolated from Raphanus sativus isunder clinical trials (Shoeb 2006).
▼
▲
▼
▲
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $40.00/5mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-17 | |
| $15.00/1KG |
Zhuozhou Wenxi import and Export Co., Ltd
|
2021-08-11 |
China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com