(3,4-Dihydroxybenzylidene)-malononitrile
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 20kg |
| Update Time: | 2019-09-06 |
Product Details
| Product Name: (3,4-Dihydroxybenzylidene)-malononitrile | CAS No.: 118409-57-7 |
| Min. Order: 1KG | Purity: 98% |
| Supply Ability: 20kg | Release date: 2019/09/06 |
Abby024
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AG 18 Basic information
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Product Name:
AG 18
Synonyms:
AG 18 - CAS 118409-57-7 - Calbiochem;TYRPHOSTIN A23 99+%;(3,4-Dihydroxybenzylidene)-malononitrile, RG-50810;AG 18 (Tyrphostin A23);2-(3,4-Dihydroxyphenyl)ethene-1,1-dicarbonitrile;4,5-Dihydroxybenzylidenemalononitrile;(3,4-Dihydroxyphenyl)methylene propanedinitrile;Propanedinitrile, ((3,4-dihydroxyphenyl)methylene)-
CAS:
118409-57-7
MF:
C10H6N2O2
MW:
186.17
EINECS:
Product Categories:
All Inhibitors;Inhibitors;Tyrosine Kinase Inhibitors;Protein Kinase;Intracellular Signaling
Mol File:
118409-57-7.mol
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AG 18 Chemical Properties
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Melting point
225°C
storage temp.
2-8°C
solubility
Soluble in DMSO, ethanol, or DMF
form
Yellow solid
λmax
464nm(DMSO)(lit.)
Stability:
Store in refrigerator
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Safety Information
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WGK Germany
3
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MSDS Information
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SigmaAldrich
English
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AG 18 Usage And Synthesis
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Chemical Properties
Yellow Powder
Uses
A specific inhibitor for the epidermal growth factor receptor. Also inhibits EGF-dependent cell proliferation (IC50=35uM)
Uses
AG 18 inhibits EGFR with IC50 of 35 μM.
Biological Activity
Inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC 50 values are 35 and 25 μ M respectively). Inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler that alters phosphorylation-dependent cell signaling.
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AG 18 Preparation Products And Raw materials
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Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com