Clioquinol Specification

Chloral hydrate dosing information

Usual Adult Dose for Insomnia:

500 mg to 1 g 15 to 30 minutes before bedtime.

Usual Adult Dose for Sedation:

250 mg 3 times daily after meals, or

500 mg to 1 g 30 minutes before surgery

Usual Pediatric Dose for Insomnia:

Oral, Rectal:

Hypnotic: 50 mg/kg/dose at bedtime

Maximum dose: 1 g/dose

Total maximum: 1 g/day for infants and 2 g/day for children

Usual Pediatric Dose for Sedation:

Neonatal: Oral, Rectal:

For sedation prior to a procedure: 25 mg/kg. Repeat doses should be used with great caution as drug and metabolites accumulate with repeated use; toxicity has been reported after 3 days in a preterm neonate and after 7 days in a term neonate receiving chloral hydrate 40 to 50 mg/kg every 6 hours.