Product Details
| Product Name:
Tipifarnib |
CAS No.:
192185-72-1 |
| Min. Order:
1kg |
Purity:
99% |
| Supply Ability:
100kg |
Release date:
2019/07/06 |
| Product NUmber: :
WM.562 |
| Tipifarnib Basic information |
| Product Name: |
Tipifarnib |
| Synonyms: |
TIPIFARNIB;TIPIFARNIB ZARNESTRA;(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone;Tipifarnib(R115777);Zarnestra;(R)-(+)-R 115777;6-[(R)-AMino(4-chlorophenyl)(1-Methyl-1H-iMidazol-5-yl)Methyl]-4-(3-chlorophenyl)-1-Methyl-2(1H)-quinolinone;Tipifarnib(Zarnestra,NSC-702818, R-115777) |
| CAS: |
192185-72-1 |
| MF: |
C27H22Cl2N4O |
| MW: |
489.4 |
| EINECS: |
|
| Product Categories: |
Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Tyrosine Kinase Inhibitors;Inhibitor;Antineoplastic;Inhibitors |
| Mol File: |
192185-72-1.mol |
 |
| |
| Tipifarnib Chemical Properties |
| Melting point |
211-213°C (dec.) |
| storage temp. |
-20?C Freezer |
| |
| Tipifarnib Usage And Synthesis |
| Chemical Properties |
Off-White to Pale Beige Solid |
| Uses |
A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation of bortezomib(B675700)-induced aggresomes. Also shown to inhibit the growth of myeloid leukemia cell lines and primary leukemia cells by inducing apoptosis and cell-cycle blockage when combined with rapamycin(R124000). |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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