Product Details
| Product Name:
Sotalol hydrochloride |
CAS No.:
959-24-0 |
| Min. Order:
1g |
Purity:
99% |
| Supply Ability:
100KG |
Release date:
2019/07/06 |
| Product：:
AD68 |
| Sotalol hydrochloride Basic information |
| Product Name: |
Sotalol hydrochloride |
| Synonyms: |
4-(2-isopropylamino-1-hydroxyaethyl)methanesulfonailidhydrochlorid;4’-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilidemonohydrochloride;4’-(1-hydroxy-2-(isopropylamino)ethyl)-methanesulfonanilidmonohydrochlorid;isopropylaminohydroxyethylmethanesulfonanilidehydrochloride;meadjohnson1999;n-isopropyl-beta-(4-methanesulfonamidophenyl)ethanolaminehydrochloride;4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilide hydrochloride;BETAPACE |
| CAS: |
959-24-0 |
| MF: |
C12H21ClN2O3S |
| MW: |
308.82 |
| EINECS: |
213-496-0 |
| Product Categories: |
Miscellaneous Natural Products;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Adrenoceptor;Amines;Aromatics;Sulfur & Selenium Compounds;EXCENEL |
| Mol File: |
959-24-0.mol |
 |
| |
| Sotalol hydrochloride Chemical Properties |
| Melting point |
218-220°C |
| storage temp. |
Store at RT |
| solubility |
H2O: 20 mg/mL |
| form |
powder |
| color |
white to off-white |
| Water Solubility |
Soluble in phosphate buffered saline, DMSO, ethanol, water, and methanol. |
| CAS DataBase Reference |
959-24-0(CAS DataBase Reference) |
| Hazard Codes |
Xi |
| Risk Statements |
36/37/38 |
| Safety Statements |
26-36 |
| WGK Germany |
3 |
| RTECS |
PB0826000 |
| Toxicity |
LD50 in male mice, rats (mg/kg): 2600, 3450 orally; 670, 680 i.p.; LD50 orally in rabbits: 1000 mg/kg; LD50 i.p. in dogs: 330 mg/kg (Lish) |
| Provider |
Language |
| SigmaAldrich |
English |
| |
| Sotalol hydrochloride Usage And Synthesis |
| Chemical Properties |
White Crystalline Solid |
| Uses |
A potent -adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period |
| Uses |
A potent α-adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period. |
| Uses |
antibacterial |
| Definition |
ChEBI: A hydrochloride salt that is the monohydrochloride of sotalol. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias. |
| Brand name |
Betapace(Berlex); Sorine (Upsher Smith). |
| Biological Activity |
A relatively potent pure β adrenergic antagonist, unique in possessing additional class III antiarrhythmic activity. Also available as part of the Mixed Adrenergic Tocriset™ . |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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