5-Chloro-2'-deoxyuridine NEW
Price | $30 | $40 |
Package | 25mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: 5-Chloro-2'-deoxyuridine | CAS No.: 50-90-8 |
Purity: 99.54% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | 5-Chloro-2'-deoxyuridine |
Description | 5-Chloro-2'-deoxyuridine (5-Chlorodeoxyuridine) is a thymine analog. It can be used to study the potential of hypochlorous acid damage to DNA and DNA precursors. |
In vitro | The mammalian cells incorporate the analog into DNA when 5-Chloro-2’-deoxyuridine (ClDU) is placed into the tissue culture medium. It is observed that a 10 μM concentration of 5-Chloro-2’-deoxyuridine in the media does not alter cell division kinetics. Previously it has been shown that 5-Chloro-2’-deoxyuridine is metabolized and incorporated into DNA using antibodies that bind selectively to DNA containing halogenated bases. In this study, 5-Chloro-2’-deoxyuridine is more similar to BrdU in acting as a T analog. The toxicity of 5-Chloro-2’-deoxyuridine could in part be attributed to inhibition of thymidylate synthase [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 125 mg/mL (475.92 mM) |
Keywords | Inhibitor | inhibit | 5Chloro2'deoxyuridine | 5-Chloro-2'-deoxyuridine | 5 Chloro 2' deoxyuridine |
Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Nucleotide Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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