Lornoxicam
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1G |
| Supply Ability: | 100KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: Lornoxicam | CAS No.: 70374-39-9 |
| Min. Order: 1G | Purity: 98% |
| Supply Ability: 100KG | Release date: 2019/07/06 |
AD68
| Lornoxicam Basic information |
| Description References |
| Product Name: | Lornoxicam |
| Synonyms: | LORNOXICAM;AKOS 93662;6-CHLORO-4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE;2h-thieno(2,3-e)-1,2-thiazine-3-carboxamide,6-chloro-4-hydroxy-2-methyl-n-2-py;chlortenoxicam;ridinyl-,1,1-dioxide;6-Chloro-4-hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide-1,1-dioxide;LornoxicamConsultedStandard |
| CAS: | 70374-39-9 |
| MF: | C13H10ClN3O4S2 |
| MW: | 371.82 |
| EINECS: | 1308068-626-2 |
| Product Categories: | APIs;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Fused Ring Systems;API;AVITA;Other APIs |
| Mol File: | 70374-39-9.mol |
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| Lornoxicam Chemical Properties |
| Melting point | 225-230°C (dec.) |
| storage temp. | -20°C Freezer |
| solubility | DMSO: >5mg/mL (warmed) |
| pka | pKa2 4.7(at 25℃) |
| color | faint yellow to dark yellow |
| Merck | 14,5582 |
| CAS DataBase Reference | 70374-39-9(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi,T+ |
| Risk Statements | 36/37/38-28 |
| Safety Statements | 26-36-45-36/37-28 |
| RIDADR | UN 2811 6.1 / PGII |
| RTECS | XJ9095000 |
| HazardClass | IRRITANT |
| PackingGroup | II |
| Toxicity | LD50 orally in mice, rats, rabbits, dogs, monkeys: >10 mg/kg (Pruss) |
| MSDS Information |
| Lornoxicam Usage And Synthesis |
| Description | Lornoxicam (Trade name: “Xefo”) belongs to a non-steroidal anti-inflammatory drug. As a kind of oxicam class drug, it has analgesic, anti-inflammatory and antipyretic properties. It can be used for the treatment of various type of acute mild to moderate pain which results from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and rheumatic diseases. Lornoxicam is capable of potently inhibiting the prostaglandin biosynthesis process, making it have highly pronounced efficacy. The exact mechanism of Lornoxicam is not exactly understood. However, it is indicated that Lornoxicam can inhibit the prostaglandin and thromboxane synthesis by inhibiting both COX-1 and COX-2, leading to reduction of inflammation, pain, fever, and swelling. |
| References | https://www.drugbank.ca/drugs/DB06725 https://en.wikipedia.org/wiki/Lornoxicam |
| Chemical Properties | Crystalline Solid |
| Uses | keratolytic, antiacne, antineoplastic |
| Uses | ocular vasoconstrictor |
| Uses | For the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases. |
| Uses | Cyclooxygenase inhibitor; structurally similar to tenoxicam. Anti-inflammatory; analgesic |
| Definition | ChEBI: A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for th treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com