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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>Rosiglitazone maleate
Rosiglitazone maleate
  • Rosiglitazone maleate

Rosiglitazone maleate

Price $1
Package 1KG
Min. Order: 1G
Supply Ability: 100KG
Update Time: 2019-07-06

Product Details

Product Name: Rosiglitazone maleate CAS No.: 155141-29-0
Min. Order: 1G Purity: 98%
Supply Ability: 100KG Release date: 2019/07/06

AD68

Rosiglitazone maleate Basic information
Product Name: Rosiglitazone maleate
Synonyms: 5-((4-[2-(METHYL-2-PYRIDINYLAMINO)-ETHOXY]-PHENYL)-METHYLENE)-2,4-THIAZOLIDINEDIONE;5-{p-[2-(methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedione maleate;ROSIGLITAZONE MALEATE;RosiglitazoneTartrate;Avandi;BRL-49653c;RSIGLITAZONEMALEATE;5-(4-(2-(Methyl(pyridin-2-yl)aMino)ethoxy)benzyl)thiazolidine-2,4-dione Maleate
CAS: 155141-29-0
MF: C22H23N3O7S
MW: 473.5
EINECS: 1312995-182-4
Product Categories: Active Pharmaceutical Ingredients;Antidiabetic;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Rosiglitazone;Heterocycles;Sulfur & Selenium Compounds;Inhibitor;API
Mol File: 155141-29-0.mol
Article illustration
 
Rosiglitazone maleate Chemical Properties
Melting point  235-240°C
storage temp.  -20°C Freezer
pka 6.1; 6.8(at 25℃)
CAS DataBase Reference 155141-29-0(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  20/21/22-36/38
Safety Statements  24/25-37/39-26
MSDS Information
 
 
Rosiglitazone maleate Usage And Synthesis
Chemical Properties White To Off-White Solid
Uses Insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR- γ).
Uses Thiazole alkanes antidiabetic drug
Uses Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. Rosiglitazone is a prototypical TZD that has served as a reference compound for this class. It is a potent and selective PPARγ ligand that binds to the PPARγ ligand-binding domain with a Kd value of 43 nM. It activates luciferase-based expression constructs PPARγ1 and PPARγ2 with EC50 values of approximately 30 nM and 100 nM, respectively. Rosiglitazone is active in vivo as an antidiabetic agent in the ob/ob mouse model, and has been used as an oral hypoglycemic agent in the treatment of type 2 diabetes in humans for many years.[Cayman Chemical]
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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