Oxolinic acid
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1G |
| Supply Ability: | 100KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: Oxolinic acid | CAS No.: 14698-29-4 |
| Min. Order: 1G | Purity: 98% |
| Supply Ability: 100KG | Release date: 2019/07/06 |
AD68
| Oxolinic acid Basic information |
| Description References |
| Product Name: | Oxolinic acid |
| Synonyms: | 1-ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylicacid;1-ethyl-6,7-methylenedioxo-4-quinoline-3-carboxlicacid;1-ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylicacid;5-g)quinoline-7-carboxylicacid,5-ethyl-5,8-dihydro-8-oxo-3-dioxolo(4;5-g]quinoline-7-carboxylicacid,5-ethyl-5,8-dihydro-8-oxo-3-dioxolo[4;dioxacin;emyrenil;gramurin |
| CAS: | 14698-29-4 |
| MF: | C13H11NO5 |
| MW: | 261.23 |
| EINECS: | 238-750-8 |
| Product Categories: | Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;veterinary medicine,APIs,pharmaceutical raw material;UTIBID;API |
| Mol File: | 14698-29-4.mol |
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| Oxolinic acid Chemical Properties |
| Melting point | 314-316°C (dec.) |
| Boiling point | 473℃ |
| Fp | >110°(230°F) |
| storage temp. | 2-8°C |
| solubility | Soluble in 0.5N NaOH with warming |
| form | Crystalline Powder |
| color | White |
| Sensitive | Light Sensitive |
| Merck | 13,7014 |
| Stability: | Stable. Combustible. |
| CAS DataBase Reference | 14698-29-4(CAS DataBase Reference) |
| EPA Substance Registry System | 1,3-Dioxolo[4,5- g]quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo- (14698-29-4) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-24/25-60-36 |
| WGK Germany | 3 |
| RTECS | JI5075000 |
| F | 10 |
| Hazardous Substances Data | 14698-29-4(Hazardous Substances Data) |
| Toxicity | LD50 in mice, rats (mg/kg): >6000, >2000 orally (Turner) |
| Oxolinic acid Usage And Synthesis |
| Description | Developed in Japan in the 1970s, oxolinic acid belongs to the family of quinolone antibiotic, which is a synthetic antimicrobial agent aiming at gram-negative bacteria, especially those responsible for urinary tract infections. It is also commonly used in clinical for microbiological antimicrobial susceptibility tests against gram negative microbial isolates, providing antibiotic treatment options for infected patients. It can serve as a selective agent in several types of isolation media, for example, to isolate Gardnerella vaginalis. Besides, oxolinic acid can be applied in agriculture, which has proved to be effective against the seed-borne pathogen, such as Burkholderia glumae, a bacteria inducing grain rot, sheath rot, seedling rot, and bacterial panicle blight. Oxolinic acid works by targeting DNA gyrase or topoisomerase II, enzymes vital for DNA synthesis, which ultimately inhibits DNA synthesis and cell division. |
| References | https://en.wikipedia.org/wiki/Oxolinic_acid http://www.toku-e.com/product/oxolinic_acid/ https://www.goldbio.com/product/3027/oxolinic-acid |
| Chemical Properties | Crystalline Solid |
| Uses | Oxolinic acid is a quinolone antibiotic used for studies on DNA winding and coiling and for studies on dopaminergic neurotransmission processes. It is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia |
| Uses | Quinolone antibacterial. |
| Definition | ChEBI: A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the tr atment of bacterial infections in cattle, pigs and poultry. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com