Product Overview: 4,6-Dichloro-5-methoxy-2-methylpyrimidine

Product Name: 4,6-Dichloro-5-methoxy-2-methylpyrimidine

CAS Number: 851986-00-0

Product Description:

4,6-Dichloro-5-methoxy-2-methylpyrimidine is an organic compound belonging to the class of pyrimidine derivatives. It features a pyrimidine ring with two chlorine atoms substituted at positions 4 and 6, a methoxy group (-OCH3) at position 5, and a methyl group (-CH3) attached to the nitrogen atom of the pyrimidine ring. This versatile molecule exhibits unique physical and chemical properties, making it a valuable intermediate in various industrial applications.

Physical Properties:

• Appearance: White to off-white crystalline solid

• Melting Point: (Approximate) Depending on purity, can range from moderate to high temperatures

• Boiling Point: Decomposes before reaching boiling point

• Solubility: Soluble in polar organic solvents such as DMSO, DMF, and acetone; insoluble or poorly soluble in water

• Stability: Stable under normal conditions, but may be sensitive to light, heat, and moisture

Chemical Properties:

• 4,6-Dichloro-5-methoxy-2-methylpyrimidine is a reactive intermediate due to the presence of halogen substituents and the electron-rich pyrimidine ring.

• It can undergo substitution reactions at the halogenated positions, as well as nucleophilic attacks on the pyrimidine ring.

• The methoxy group and methyl substituent influence the reactivity and selectivity of these reactions.

Application Areas:

• Pharmaceutical Industry: As a key intermediate in the synthesis of bioactive compounds and drug candidates.

• Agricultural Chemicals: Used in the development of pesticides, herbicides, and fungicides.

• Dye and Pigment Industry: As a building block for the synthesis of specific dyes and pigments with unique color properties.

• Polymer Additives: Potential use as a monomer or modifier in the production of functional polymers.

Upstream Products:

• Starting materials for the synthesis of 4,6-dichloro-5-methoxy-2-methylpyrimidine include substituted pyrimidine derivatives, halogenating agents, methylating agents, and methoxylation reagents.

• The specific upstream products depend on the chosen synthesis route.

Downstream Products:

• The main downstream products are the final chemicals or formulations incorporating 4,6-dichloro-5-methoxy-2-methylpyrimidine as an intermediate.

• These include pharmaceutical actives, agrochemicals, dyes, pigments, and possibly other specialty chemicals.

Safety Precautions:

• Handling: Wear appropriate personal protective equipment (PPE) including chemical-resistant gloves, goggles, and lab coat. Avoid direct contact with skin, eyes, and clothing.

• Storage: Store in a cool, dry, well-ventilated area away from direct sunlight, heat, and incompatible materials.

• Fire Hazard: This compound may be flammable or decompose to flammable products upon exposure to heat or flame. Keep away from ignition sources.

• Health Hazards: Inhalation, ingestion, or skin/eye contact may cause irritation or more serious health effects. Follow safe handling procedures and consult Material Safety Data Sheet (MSDS) for detailed information.

• Environmental Considerations: Dispose of waste material according to local regulations and environmental guidelines.

Please note that the above information is provided for general reference only. For specific safety, handling, and disposal instructions, consult the MSDS or contact the supplier directly.