4-Amino-3,5-dichloroacetophenone NEW
Price | Get Latest Price | ||
Package | 1KG | 5KG | 25KG |
Min. Order: | 1KG |
Supply Ability: | 20 T each week |
Update Time: | 2023-08-13 |
Product Details
Product Name: 4-Amino-3,5-dichloroacetophenone | CAS No.: 37148-48-4 |
EC-No.: 253-368-1 | Min. Order: 1KG |
Purity: 98%~99% | Supply Ability: 20 T each week |
Release date: 2023/08/13 |
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Product Name: | 4-Amino-3,5-dichloroacetophenone |
Synonyms: | 1-(4-Amino-3,5-dichlorophenyl)-ethanone, 3,5-Dichloro-4-aminoacetophenone;1-(4-Amino-3,5-dichloro-phenyl)-2-ethanone;5-AMINO-3,5-DICHLORO ACETOPHENONE;4''-AMINO-3'',5''-DICHLOROACETOPHENONECLENBUTEROL;4-Amino-3,5-dichloroacetophenone,98%;4′-Amino-3′,5′-dichloroacetophenone,1-(4-Amino-3,5-dichlorophenyl)-ethanone, 3,5-Dichloro-4-aminoacetophenone;3,5-dichloro-p-aMino acetophenone;4-AMino-3,5-dichloroacetophenone, 98% 5GR |
CAS: | 37148-48-4 |
MF: | C8H7Cl2NO |
MW: | 204.05 |
EINECS: | 253-368-1 |
Product Categories: | Chemical Amines;Amines;Aromatic Acetophenones & Derivatives (substituted);(intermediate of leflunomide);Aromatics;37148-48-4 |
Mol File: | 37148-48-4.mol |
4-Amino-3,5-dichloroacetophenone Chemical Properties |
Melting point | 162-166 °C(lit.) |
Boiling point | 351.5±42.0 °C(Predicted) |
density | 1.2748 (rough estimate) |
refractive index | 1.5500 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | -1.72±0.10(Predicted) |
color | Light Tan to Brown |
InChI | InChI=1S/C8H7Cl2NO/c1-4(12)5-2-6(9)8(11)7(10)3-5/h2-3H,11H2,1H3 |
InChIKey | JLPKZJDZXIKSCP-UHFFFAOYSA-N |
SMILES | C(=O)(C1=CC(Cl)=C(N)C(Cl)=C1)C |
CAS DataBase Reference | 37148-48-4(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-37/39 |
WGK Germany | 3 |
HS Code | 29223990 |
4-Amino-3,5-dichloroacetophenone Usage And Synthesis |
Description | 4-Amino-3,5-dichloroacetophenone is an intermediate in the synthesis of the antitussive and antiasthmatic drug gramtin. |
Storage | 4-Amino-3,5-dichloroacetophenone should be stored in a cool, dry place in a small, well filled, well-closed container, protected from light. When a partially filled container is used, the air should be replaced by nitrogen or another inert gas. 4-Amino-3,5-dichloroacetophenone oxidizes on exposure to air, resulting in an increase in the peroxide value. |
Chemical Properties | 4-Amino-3,5-dichloroacetophenone is a white to light yellow crystal powder. Insoluble in cold water, slightly soluble in hot water. |
Uses | 4-Amino-3,5-dichloroacetophenone is used to synthesize the drug Clenbuterol. Clenbuterol is a steroid-like chemical that was initially developed to treat asthma in horses, working by relaxing the airways in the animals'lungs. |
Preparation | 4-Amino-3,5-dichloroacetophenone was synthesized by chlorination of 4-aminoacetophenone. Add 4-aminoacetophenone and acetic acid (80%) into the reaction pot, stir and dissolve, quickly add chlorine-containing glacial acetic acid solution, the temperature of the addition is 5°C. After the addition is completed, immediately put into ice water to precipitate, filter, and wash with water to obtain the crude product. Recrystallize with ethanol to obtain the finished product of 4-Amino-3,5-dichloroacetophenone. |
Application | 4-Amino-3,5-dichloroacetophenone is a compound useful in organic synthesis. |
4-Amino-3,5-dichloroacetophenone Preparation Products And Raw materials |
Raw materials | Acetic acid-->4-Aminoacetophenone-->Acetic anhydride-->Chlorine-->Acetyl chloride-->2,6-Dichloroaniline-->2,4,6-Trichloroaniline |
Preparation Products | 4-AMINO-ALPHA-TERT-BUTYLAMINE-3,5-DICHLOROACETOPHENONE-->4-Amino-3,5-dichloro-alpha-bromoacetophenone-->1-(4-AMINO-3-CHLORO-PHENYL)-ETHANONE-->Clenbuterol hydrochloride-->3,4,5-TRICHLORO-BENZOICACID-->3',5'-Dichloroacetophenone |
Company Profile Introduction
Shandong Huisheng Import & Export Co., Ltd. is located in Jinan city, Shandong Province, is a collection of domestic trade, international trade in one of the diversified services company. Our goal is to provide customers with high quality solutions and one-stop purchasing experience. At present, the company business scope involves five areas: Organic chemical raw materials, inorganic chemical raw materials, fine chemical raw materials, dangerous chemicals and green environmental protection chemical technology project promotion, and we has also established good relations of cooperation with several well-known enterprises and won the strong support of extensive trust from the new and old customers.
Products are widely used in automobile, household appliances, office supplies, mobile phone accessories, routers, food, medical and other fields. At present, our business covers 30 countries, and our customers mainly come from Australia, New Zealand, Canada, Germany, France, Poland, South Korea, Russia, Bangladesh, Vietnam, Kazakhstan, India, Ghana, Nigeria, South Africa, Egypt and other more than 30 countries.
The company has a sound quality management system and advanced professional equipment, with a positive attitude to meet the changing needs of customers. We take "quality products, quality service, competitive price, timely delivery" as the purpose, looking forward to greater cooperation with overseas customers on the basis of mutual benefit.
Our company provides a wide range of products to meet your various needs. Since its inception, the company has always adhered to the "quality first, customer first, reputation first" business policy, wholeheartedly meet the potential needs of our customers. Under the irresistible situation of economic globalization, our company is willing to cooperate sincerely with enterprises around the world to achieve a win-win situation.
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