4-AMINO-2-CHLORO-5-IODOPYRIMIDINE NEW
| Price | Get Latest Price |
| Package | 200kg |
| Min. Order: | 200kg |
| Supply Ability: | 20 tons |
| Update Time: | 2025-04-02 |
Product Details
| Product Name: 4-AMINO-2-CHLORO-5-IODOPYRIMIDINE | CAS No.: 597551-56-9 |
| Min. Order: 200kg | Purity: 0.99 |
| Supply Ability: 20 tons | Release date: 2025/04/02 |
4-Amino-2-chloro-5-iodopyrimidine CAS 597551-56-9 | Core Supplier of Highly Reactive Iodopyrimidine Intermediates
[Core Keywords]: 4-Amino-2-chloro-5-iodopyrimidine Supplier, CAS 597551-56-9, Iodopyrimidine Pharmaceutical Intermediate, Building Blocks for Targeted Drug Synthesis
Product Basic Information
Chemical Name: 4-Amino-2-chloro-5-iodopyrimidine
CAS Number: 597551-56-9 (Keyword Emphasis)
Molecular Formula: C4H3ClIN3
Appearance: Off-white to light yellow crystalline powder
Purity: ≥98.0% (HPLC, Pharmaceutical Intermediate Grade)
Key Physical and Chemical Properties (Structured Data Optimization)
| Property | Parameter Value |
|---|---|
| Molecular Weight | 271.44 g/mol |
| Melting Point | 185-188°C (Decomposition, DSC Determination) |
| Solubility | Soluble in DMSO, DMF; Slightly soluble in methanol; Insoluble in water |
| Stability | Light-sensitive (Store in dark), Stable at pH 5-8 |
| Storage Conditions | -20°C, protected from light, under inert gas |
Upstream and Downstream Industry Chain Integration
? Upstream Raw Material Assurance
Core Intermediates: 4-Amino-2-chloropyrimidine, Iodinating Reagents (e.g., N-Iodosuccinimide)
Process Optimization: Selective Iodination Technology (Conversion Rate >90%, By-products <0.5%)
? Downstream Application Expansion
Anticancer Drugs: Kinase Inhibitor Radioisotope-labeled Precursors
Molecular Probes: DNA/RNA-targeted Covalent Inhibitor Synthesis
Diagnostic Reagents: PET Imaging Agent Linker Modules
Agricultural Chemicals: Structural Optimization of Novel Fungicides
Industry Solutions and Technical Advantages
| Application Area | Typical Scenario | Technical Advantages |
|---|---|---|
| Targeted Therapy | EGFR-TKI Resistance Mutant Inhibitor Development | Iodine Atom Click Chemistry Coupling Efficiency >95% |
| Molecular Imaging | 12?I/131I Radioisotope-labeled Drug Synthesis | Iodine Site Labeling Purity ≥99.5% |
| Chemical Biology | CRISPR-Cas9 Gene Editing Tool Modification | Amine-directed Modification Selectivity >97% |
| Agricultural Formulations | Pyrimidine Fungicide Resistance Mutant Inhibitor | Light Resistance (Stability >85% under UV 254nm) |
SEO Keyword Matrix
Core Keywords:
"4-Amino-2-chloro-5-iodopyrimidine Price"
"CAS 597551-56-9 Technical Parameters"
"Highly Reactive Iodopyrimidine Supplier"
Long-tail Keyword Combinations:
"Radioisotope-labeled Drug Intermediate Manufacturer"
"Kinase Inhibitor Iodinated Precursor Supplier"
"cGMP Grade 597551-56-9 Manufacturer"
Quality Certification and Compliance
? cGMP Compliant Production: Complies with ICH Q7 Active Pharmaceutical Ingredient (API) Intermediate Standards
? Radioisotope Labeling Support: Provides Custom 12?I/131I Isotope Labeling Services (Requires Special Qualifications)
? Analytical Reports: Full Set of Documents Including HPLC, MS, and Elemental Analysis
? Global Logistics: UN 2910 Radioactive Material Transportation Packaging (Optional, Requires Additional Agreement)
Company Profile Introduction
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China- Since: 2004-04-13
- Address: No. 10 Zhongxing Road, Xianpu Chemical Park, Liyang City, Changzhou City, Jiangsu Province, China