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Postion:Product Catalog >API>Circulatory system drugs>Angina Pectoris Drugs>Amlodipine besilate 111470-99-6
Amlodipine besilate  111470-99-6
  • Amlodipine besilate  111470-99-6

Amlodipine besilate 111470-99-6

Price $20
Package 1KG
Min. Order: 10G
Supply Ability: 10MT
Update Time: 2019-01-15

Product Details

Product Name: Amlodipine besilate 111470-99-6 CAS No.: 111470-99-6
Min. Order: 10G Purity: 99%
Supply Ability: 10MT Release date: 2019/01/15
MF : C26H31ClN2O8S Appearance : White Crystalline Solid
Usage: A dihydropyridine calcium channel blocker

CAS 111470-99-6

 

 

Product Name

Amlodipine besilate

Alias

mono benzene sulfonate

CAS

111470-99-6

MF

C26H31ClN2O8S

MW

567.05

Purity

99%

Appearance

White Crystalline Solid

Certification

ISO 9001, USP, BP

Standard

BP Standard

Usage

A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive

Packing

Discreet packing ways as your requirement, 100% go through

Storage

Store in cool and dry area and keep away from direct sunlight

 

 

 

Specification:

Item

Specification

 

Result

Appearance

White or almost white powder

 

Complies

Identification

IR spectrum is in conformance with that of RSThe retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay

Complies

Optical rotation

-0.10°~+0.10°

 

+0°

Water

≤0.5%

 

0.10%

Residue on ignition

≤0.02%

 

0.004%

Related substances

TLC method: any impurity ≤0.3%, at most 2 impurities more than 0.1%

Complies

HPLC method: amlodipine impurity A ≤0.3%
Total of other impurity ≤0.3%

 

Impurity A=0.002%
Total of other impurity= 0.05%

Residual solvent

Ethanol ≤2000pm (loss on drying)

 

500ppm

Microbiological test

 

Total aerobic microbial count: ≤1X10²CFU/g


Total molds and yeast count: 1X10²CFU/g


E.coli: absert(1g)

10CFU/G


10CFU/G


Absent

Assay

97.0%~102.0%

 

100.1%

Conclusion

 

The results conforms with USP31

 

 

 

Use:

 

 

1.A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive.


2.Angiotensin II inhibitor prodrug, antihypertensive.


3.Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.

 

 

Description:

 

 

Amlodipine (generic name Amlodipine Besylate) is a class of calcium channel blockers.
Amlodipine functionalizes by the dilation of blood vessels and the improvement of blood flow, which lead to lowered blood pressure. Thereby, it is used to treat high bold pressure (hypertension). Lowering high blood pressure also reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions, and kidney problems. Amlodipine is also used to prevent certain types of chest pains (angina), which may help to increase the ability to exercise and decrease the frequency of angina attacks. Amlodipine can be used to treat coronary artery disease (CAD) including chronic stable angina, vasospastic angina, and angiographically documented CAD.

 

 

Advantages:

 

 

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.


1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.

 

Amlodipine besilate  111470-99-6   Pharmaceutical Raw Materials

 Amlodipine besilate  111470-99-6   Pharmaceutical Intermediate

Amlodipine besilate  111470-99-6   Raw Chemical Product

Amlodipine besilate  111470-99-6   Supplier & manufactuer 

 

Company Profile Introduction

Hubei XinRunde Chemical Co., Ltd covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Products sell well all over the country and exported to Europe and the United States and Southeast Asia,and so on.

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