3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfoNamide NEW
Price | Get Latest Price |
Package | 1kg |
Min. Order: | 1kg |
Supply Ability: | 200kg |
Update Time: | 2023-11-01 |
Product Details
Product Name: 3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfoNamide | CAS No.: 1228779-96-1 |
Min. Order: 1kg | Purity: 99% |
Supply Ability: 200kg | Release date: 2023/11/01 |
3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfoNamide
It is a chemical compound with the molecular formula C12H17N3O5S and the CAS number 1228779-96-1.
It is a white or off-white solid with a melting point of 165-167°C.
It is used as an intermediate for the synthesis of venetoclax, a Bcl-2 inhibitor for the treatment of various cancers.
Venetoclax, also known as ABT-199 or GDC-0199, is a potent and selective oral drug that binds to Bcl-2 and induces apoptosis in cancer cells.
It was approved by the FDA in 2016 for chronic lymphocytic leukemia, non-Hodgkin lymphoma, small lymphocytic lymphoma, diffuse large B-cell lymphoma and multiple myeloma.
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