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Postion:Product Catalog >Analytical Chemistry>Standard>Pharmaceutical Impurity Reference Standards>3-?Isoquinolinecarboxyl?ic acid, 4-?hydroxy-?1-?methyl-?7-?phenoxy-?, ethyl ester
3-?Isoquinolinecarboxyl?ic acid, 4-?hydroxy-?1-?methyl-?7-?phenoxy-?, ethyl ester
  • 3-?Isoquinolinecarboxyl?ic acid, 4-?hydroxy-?1-?methyl-?7-?phenoxy-?, ethyl ester

3-?Isoquinolinecarboxyl?ic acid, 4-?hydroxy-?1-?methyl-?7-?phenoxy-?, ethyl ester NEW

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 200kg
Update Time: 2023-11-01

Product Details

Product Name: 3-?Isoquinolinecarboxyl?ic acid, 4-?hydroxy-?1-?methyl-?7-?phenoxy-?, ethyl ester CAS No.: 1421312-34-6
Min. Order: 1kg Purity: 99%
Supply Ability: 200kg Release date: 2023/11/01

3-Isoquinolinecarboxylic acid, 1-chloro-4-hydroxy-7-phenoxy-, methyl ester 

It is a white to off-white crystalline solid with a molecular weight of 285.69 g/mol and a melting point of 136-138 °C. 

It is soluble in organic solvents such as methanol, ethanol, acetone and dichloromethane. 

It is an intermediate for the synthesis of roxadustat, a drug for the treatment of anemia associated with chronic kidney disease. 

Roxadustat is an oral inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH), which stimulates erythropoiesis by increasing the production of erythropoietin and iron absorption. 

Roxadustat is marketed in China and Japan and is under development in other countries.


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Our company specializes in the research, development and production of APIs and pharmaceutical intermediates. At the same time, our core R&D team has more than 20 years of drug R&D experience. Under the support of a good research and development environment and a professional technical team, our company has obtained rich experience and outstanding achievements of new drugs and generic drugs projects. On the one hand, we are focused on the research and development and the optimization of production processes of generic drugs such as anti-viral and anti-malaria. On the other hand, we are also committed to the cooperative development of innovative drugs in the fields of respiratory system and hypoglycemia. We can provide technical support in all key links of drug research and development for drug production and distribution companies.

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  • Address: 1306 Block A, Dragon Times Building, 18 Wantang Road, Hangzhou,310013 CHINA
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