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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyridine compound>Bromopyridine>2,5-Dibromopyridine
2,5-Dibromopyridine
  • 2,5-Dibromopyridine
  • 2,5-Dibromopyridine
  • 2,5-Dibromopyridine
  • 2,5-Dibromopyridine
  • 2,5-Dibromopyridine

2,5-Dibromopyridine NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-09-12

Product Details

Product Name: 2,5-Dibromopyridine CAS No.: 624-28-2
EC-No.: 210-839-6 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/09/12

CAS:624-28-2
MF:C5H3Br2N
MW:236.89
EINECS:210-839-6
Product Categories:alkyl bromide;Building Blocks;C5;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Aromatics Compounds;Bromopyridines;Halopyridines;Pyridine series;Aromatics;Bases & Related Reagents;Nucleotides;Brominated heterocyclic series;Nitrogen cyclic compounds;blocks;Bromides;Pyridines;pyridine derivative;Pyridines, Pyrimidines, Purines and Pteredines;Halides;Pyridine;Pyridines derivates;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;bc0001;624-28-2
Mol File:624-28-2.mol
Article illustration

2,5-Dibromopyridine Chemical Properties
Melting point 92-95 °C (lit.)
Boiling point 235 °C / 772mmHg
density 2.0383 (rough estimate)
refractive index 1.5800 (estimate)
Fp 62℃
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka-1.57±0.10(Predicted)
form Crystalline Powder
color Almost white or light beige to brown
Water Solubility insoluble
BRN 109099
InChIInChI=1S/C5H3Br2N/c6-4-1-2-5(7)8-3-4/h1-3H
InChIKeyZHXUWDPHUQHFOV-UHFFFAOYSA-N
SMILESC1(Br)=NC=C(Br)C=C1
CAS DataBase Reference624-28-2(CAS DataBase Reference)
2,5-Dibromopyridine Usage And Synthesis
Chemical Properties2,5-Dibromopyridine is an off-white crystalline solid. It is insoluble in water but soluble in strong polar organic solvents. It exhibits strong alkalinity.
Uses2,5-Dibromopyridine (cas# 624-28-2) is a compound useful in organic synthesis.
PreparationTo synthesize 2,5-dibromopyridine, follow these steps:
Add 2-amino-5-bromopyridine (13.0 kg) into a water-cooled solution at 10 °C.
Slowly add 47% aqueous hydrogen bromide (37 L) to the mixture.
Introduce liquid bromine (11 L) into the mixture.
Maintain the reaction temperature below 10 °C.
Prepare a solution of NaNO2 (16.1 kg) and H2O (19 L) and add it dropwise to the mixture while keeping the temperature between 0-5 °C.
Stir the reaction mixture for 30 minutes.
Treat the mixture with a solution of NaOH (28.0 kg) in water (30 L) at a controlled rate below 20-25 °C.
Extract the reaction mixture with diethyl ether (3 × 40 L).
Dry the organic layer with anhydrous Na2SO4.
Remove the desiccant by filtration.
Evaporate the resulting filtrate under reduced pressure to dryness.
Suspend the residue in heptane (10 L).
Collect the target product molecule, 2,5-dibromopyridine, by filtration.
Synthesis method of 2,5-dibromopyridine

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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  • Since: 2017-12-08
  • Address: Building A, Enjoy city, Zhongshan East Road, Shijiazhuang city, Hebei province
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