2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- NEW
Price | Get Latest Price |
Package | 25kg |
Min. Order: | 1kg |
Supply Ability: | 2000ton |
Update Time: | 2024-04-12 |
Product Details
Product Name: 2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- | CAS No.: 404951-53-7 |
Min. Order: 1kg | Purity: 99% |
Supply Ability: 2000ton | Release date: 2024/04/12 |
Appearance: White powder |
Treatment of NDHF cells with Danosat not only resulted in the expected G1-S growth arrest, but also significantly reduced cell accumulation in S-phase cells as well as at the G2-M checkpoint. Danosat induces apoptosis and death of human tumor cells. Danosat increases acetylation of histones H3 and H4. Danosat inhibits HDAC1 with an IC50 of 9nM. Danosat (10 and 20nM) inhibited the proliferation of 32D cells expressing AML fusion proteins. Danosat impels the short-term implantable potential of leukemia stem cells. Danosat depletes the in vitro self-renewal potential of AML1/ETO and PLZF/ RARα-positive HSCS in mice.
Storage Condition | Keep in a cool and dry place |
Transportation | By Sea or by Air(DHL/UPS/TNT/FEDEX/EMS) |
Delivery Time | 7-28 days |
Payment | T/T, Western Union or Bitcoin |
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- Since: 2020-08-05
- Address: 804, Unit 2, Building 4, i City, No. 11, South Tangyan Road, High-tech Zone, Xi 'an, Shaanxi