2'-O-Methylguanosine
Price | Get Latest Price |
Package | 1g |
Min. Order: | 1g |
Supply Ability: | 100kg |
Update Time: | 2024-08-08 |
Product Details
Product Name: 2'-O-Methylguanosine | CAS No.: 2140-71-8 |
Min. Order: 1g | Purity: 98% |
Supply Ability: 100kg | Release date: 2024/08/08 |
Melting point | 227-231°C (dec.) |
---|---|
Density | 1.98±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | Aqueous Base (Slightly), DMSO (Slightly), |
form | Powder |
color | White to Off-white |
CAS DataBase Reference | 2140-71-8(CAS DataBase Reference) |
Description
2''-O-Methylguanosine is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase, using S-adenosyl-L-methionine (Item Nos. 16376 | 13956) as a substrate. Through its interaction with other modified nucleosides, 2''-O-methylguanosine is thought to stabilize the structure of the tRNA. 2''-O-Methylguanosine can also be found in rRNA. Normal and modified nucleosides, including 2''-O-methylguanosine, have been shown to be secreted by a natural suppressor cell line and induce apoptosis in K562/Molt4 target cells.
Company Profile Introduction
Founded in Beijing in 2006, Okeanos was born with high-tech genes specialized in molecular diagnostic reagents, vaccine raw materials, pharmaceutical intermediates and APIs with applications in the diverse fields of IVD, biomedical imaging, DNA&RNA synthesis, high-throughput sequencing and nucleic acid therapeutics. Okeanos has spearheaded the pioneering research work in nucleic acid and dye chemistry for 16 years, achieving numerous original breakthroughs as evidenced by the culmination of more than 70 patents.
In 2017, Huana Biomedical was established as the wholly-owned subsidiary of Okeanos in Hefei City, Anhui Province. The manufacture and office space is more than 60,000㎡complete with GMP compliant plants. Quality policy meet the expectations of NMPA, FDA, EDQM,PMDA,etc. Huana has an annual output of 8000L dNTPs, 20000L rNTPs (including?Pseudouridine and N-methyl-Pseudouridine), 60 tons of phosphoramidites and 20 tons of other modified nucleoside items.
Driving our success is our commitment to quality and excellence. We look forward to advancing scientific discoveries and delivering groundbreaking treatments to patients.
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- Since: 2017-11-16
- Address: Limited Liability Company
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