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Postion:Product Catalog >2-Aminothiazole
2-Aminothiazole
  • 2-Aminothiazole
  • 2-Aminothiazole

2-Aminothiazole NEW

Price $6 $0.2
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-03-29

Product Details

Product Name: 2-Aminothiazole CAS No.: 96-50-4
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/03/29
Lead time: In stock, ready for shipment Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea Origin: Manufacturer, advantage product
COA, MSDS: Available, contact us for details Name: Tina

 1. Materials information

Names

Name1,3-thiazol-2-amine
SynonymMore Synonyms

 2-Aminothiazole Biological Activity

DescriptionAminothiazole (2-Aminothiazole) is a beginning point for synthesis of many compounds including sulfur drugs, biocides, fungicides, dyes and chemical reaction accelerators.IC50 value:Target:2-Aminothiazole can be used as a thyroid inhibitor in the treatment of hyperthyroidism and it has antibacterial activity. Also used as the acid tartrate. Recent studies using prion-infected neuroblastoma cell lines have suggested that aminothiazole may be used as a therapeutic drug for prion diseases.
Related Catalog
Signaling Pathways >> Others >> Others
Research Areas >> Others
References

[1]. Gallardo-Godoy A, et al. 2-Aminothiazoles as therapeutic leads for prion diseases. J Med Chem. 2011 Feb 24;54(4):1010-21.

 Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point216.4±9.0 °C at 760 mmHg
Melting Point91-93 °C(lit.)
Molecular FormulaC3H4N2S
Molecular Weight100.142
Flash Point84.7±18.7 °C
Exact Mass100.009521
PSA67.15000
LogP0.38
Vapour Pressure0.1±0.4 mmHg at 25°C
Index of Refraction1.645
Water Solubility100 g/L (20 oC)

 MSDS

2-Aminothiazole MSDS(Chinese)

 Toxicological Information

CHEMICAL IDENTIFICATION

  • RTECS NUMBER :

  • XJ2100000

  • CHEMICAL NAME :

  • Thiazole, 2-amino-

  • CAS REGISTRY NUMBER :

  • 96-50-4

  • LAST UPDATED :

  • 199806

  • DATA ITEMS CITED :

  • 16

  • MOLECULAR FORMULA :

  • C3-H4-N2-S

  • MOLECULAR WEIGHT :

  • 100.15

  • WISWESSER LINE NOTATION :

  • T5N CSJ BZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 480 mg/kg

  • TOXIC EFFECTS :

  • Behavioral - tremor Behavioral - coma Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 570 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intraperitoneal

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 200 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LDLo - Lowest published lethal dose

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Mammal - cat

  • DOSE/DURATION :

  • 120 mg/kg

  • TOXIC EFFECTS :

  • Behavioral - tremor Behavioral - coma Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - rabbit

  • DOSE/DURATION :

  • 370 mg/kg

  • TOXIC EFFECTS :

  • Behavioral - tremor Behavioral - coma Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LDLo - Lowest published lethal dose

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - guinea pig

  • DOSE/DURATION :

  • 120 mg/kg

  • TOXIC EFFECTS :

  • Behavioral - tremor Behavioral - coma Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - rabbit

  • DOSE/DURATION :

  • 4500 mg/kg/56D-I

  • TOXIC EFFECTS :

  • Liver - hepatitis (hepatocellular necrosis), zonal Liver - fatty liver degeneration Related to Chronic Data - death

  • TYPE OF TEST :

  • TCLo - Lowest published toxic concentration

  • ROUTE OF EXPOSURE :

  • Inhalation

  • SPECIES OBSERVED :

  • Rodent - rabbit

  • DOSE/DURATION :

  • 200 mg/m3/7H/61D-I

  • TOXIC EFFECTS :

  • Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Lungs, Thorax, or Respiration - dyspnea Related to Chronic Data - death

  • TYPE OF TEST :

  • TCLo - Lowest published toxic concentration

  • ROUTE OF EXPOSURE :

  • Inhalation

  • SPECIES OBSERVED :

  • Rodent - guinea pig

  • DOSE/DURATION :

  • 200 mg/m3/7H/30D-I

  • TOXIC EFFECTS :

  • Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - chronic pulmonary edema Related to Chronic Data - death

  • TYPE OF TEST :

  • TCLo - Lowest published toxic concentration

  • ROUTE OF EXPOSURE :

  • Inhalation

  • SPECIES OBSERVED :

  • Rodent - guinea pig

  • DOSE/DURATION :

  • 25 mg/m3/7H/62D-I

  • TOXIC EFFECTS :

  • Lungs, Thorax, or Respiration - chronic pulmonary edema Liver - fatty liver degeneration Related to Chronic Data - death

MUTATION DATA

  • TYPE OF TEST :

  • Mutation in mammalian somatic cells

  • TEST SYSTEM :

  • Rodent - mouse Lymphocyte

  • DOSE/DURATION :

  • 557 mg/L

  • REFERENCE :

  • MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 155,17,1985

 Safety Information

SymbolArticle illustration
GHS07
Signal WordWarning
Hazard StatementsH302
Precautionary StatementsP301 + P312 + P330
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard CodesXn:Harmful
Risk PhrasesR22;R36/37
Safety PhrasesS26-S36/37-S39
RIDADR2811
WGK Germany3
RTECSXJ2100000
Packaging GroupI; II; III
HS Code2934999090

 Synthetic Route

Previous 1/14 Next
Article illustration

(2E)-3-Methoxya...

60838-50-8

Article illustration

Sodium acetate

127-09-3

Article illustration

thiourea

17356-08-0

~72%

Article illustration

2-Aminothiazole

96-50-4

Literature: Larsen, Robert D.; King, Anthony On-Ping Patent: US2004/23977 A1, 2004 ; Location in patent: Page/Page column 7; 8 ; US 20040023977 A1
Article illustration

2-acetamidothia...

2719-23-5

~87%

Article illustration

2-Aminothiazole

96-50-4

Literature: Sultane, Prakash R.; Mete, Trimbak B.; Bhat, Ramakrishna G. Organic and Biomolecular Chemistry, 2014 , vol. 12, # 2 p. 261 - 264
Article illustration

2-Azidothiazole

58822-97-2

~98%

Article illustration

2-Aminothiazole

96-50-4

Literature: Pagoti, Sreenivasarao; Surana, Subham; Chauhan, Ajay; Parasar, Bibudha; Dash, Jyotirmayee Catalysis Science and Technology, 2013 , vol. 3, # 3 p. 584 - 588

 Precursor & DownStream

Precursor  9

Previous 1/3 Next

  • Article illustration CAS#:60838-50-8
    (2E)-3-Methoxya...

  • Article illustration CAS#:127-09-3
    Sodium acetate

  • Article illustration CAS#:2719-23-5
    2-acetamidothiazole

  • Article illustration CAS#:58822-97-2
    2-Azidothiazole

DownStream  10

Previous 1/3 Next

  • Article illustration CAS#:109172-21-6
    3-(1,3-thiazol-...

  • Article illustration CAS#:37422-56-3
    5-methyl-4-(2-t...

  • Article illustration CAS#:557-30-2
    glyoxime

  • Article illustration CAS#:57738-11-1
    1-(6-methylimid...

 Customs

HS Code2934100090
Summary2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%


2. Packaging of materials

  • For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

  • For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                             Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping & Delivery

  • By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

Article illustration


  • By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

Article illustration


  • By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 15225627621

WhatsApp/Skype/Wechat/LINE: 86 15225627621








Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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