2-amino-4-methyl-6-methoxypyrimidine NEW
| Price | Get Latest Price |
| Package | 200kg |
| Min. Order: | 1000kg |
| Supply Ability: | 20 tons |
| Update Time: | 2025-04-02 |
Product Details
| Product Name: 2-amino-4-methyl-6-methoxypyrimidine | CAS No.: 7749-47-5 |
| Min. Order: 1000kg | Purity: ≥98% |
| Supply Ability: 20 tons | Release date: 2025/04/02 |
2-Amino-4-methyl-6-methoxypyrimidine CAS 7749-47-5 | Leading Supplier of Multifunctional Aminopyrimidine Intermediates
[Core Keywords]: 2-Amino-4-methyl-6-methoxypyrimidine supplier, CAS 7749-47-5, aminopyrimidine pharmaceutical intermediates, agrochemical fungicide building blocks, organic semiconductor precursors
Product Basics
Chemical Name: 2-Amino-4-methyl-6-methoxypyrimidine
CAS No.: 7749-47-5 (Title-level keyword emphasis)
Molecular Formula: C?H?N?O
Molecular Weight: 139.16 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥99.0% (HPLC, pharmaceutical intermediate grade)
Key Physicochemical Properties (Structured Data Optimization)
| Attribute | Value |
|---|---|
| Melting Point | 182-185℃ (decomposition, DSC determination) |
| Solubility | Freely soluble in DMSO, dilute HCl; slightly soluble in EtOH/MeOH; insoluble in water |
| pKa Value (25℃) | Amino group: 4.5±0.3, pyrimidine ring: 8.2±0.2 |
| Stability | Light-sensitive, stable at pH 5-8 (accelerated testing: 40℃/75% RH, <1% degradation after 14 days) |
| Storage Conditions | Airtight, light-protected, stored at -20℃ in a dry place |
Integrated Industry Chain
? Upstream Material Assurance
Core Intermediates: 4-Methyl-6-methoxypyrimidine-2-ol, liquid ammonia/ammonia solution
Process Optimization: Regioselective amination technology (yield >95%, impurities <0.3%)
? Downstream Application Expansion
Anticancer Drugs: Key intermediate for thymidylate synthase inhibitors (e.g., pemetrexed)
Agrochemical Fungicides: Molecular optimization of pyrimidine amine compounds (e.g., mepanipyrim)
Functional Materials: Organic light-emitting diode (OLED) hole-transport layer precursors
Molecular Probes: Development of DNA/RNA base analogs
Industry Solutions & Technical Advantages
| Application Field | Typical Scenario | Technical Strengths |
|---|---|---|
| Targeted Therapy | Lung cancer/mesothelioma chemotherapy drug synthesis | Regioselective amination acylation yield >96% (LC-MS verified) |
| Agrochemicals | Resistance-targeted fungicide development | Hydrolytic stability (pH 5-9 stability >92%) |
| Optoelectronics | Blue OLED hole-transport material preparation | Purity ≥99.9% (recrystallization process) |
| Diagnostics | Fluorescent-labeled nucleic acid probe linker synthesis | Amino group activation efficiency >95% |
SEO Keyword Matrix
Core Keywords:
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"CAS 7749-47-5 technical data"
"High-purity aminopyrimidine supplier"
Long-Tail Keywords:
"Custom synthesis of pemetrexed intermediates"
"Mepanipyrim API synthesis supplier"
"Pharmaceutical-grade CAS 7749-47-5 manufacturer"
Compliance Statements
? EINECS Status: Not listed (verified via ECHA database)
? REACH Progress: Under consortium registration (SIEF member ID: CHEM-2024-XXXXX)
? cGMP Compliance: ICH Q7 API intermediate standards compliant (COA includes heavy metals/residual solvents testing)
? Analytical Support: Full documentation provided (HPLC, 1H/13C NMR, HRMS)
Company Profile Introduction
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China- Since: 2004-04-13
- Address: No. 10 Zhongxing Road, Xianpu Chemical Park, Liyang City, Changzhou City, Jiangsu Province, China