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Postion:Product Catalog >Pharmaceutical intermediates>Bulk Drug Intermediates>(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
  • (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
  • (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
  • (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
  • (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
  • (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline

(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline NEW

Price Get Latest Price
Package 1kg 10kg 50kg
Min. Order: 1kg
Supply Ability: 20 tons
Update Time: 2025-05-28

Product Details

Product Name: (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline CAS No.: 118864-75-8
EC-No.: 1806241-263-5 Min. Order: 1kg
Purity: 99.99% Supply Ability: 20 tons
Release date: 2025/05/28

(S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline can be used to prepare solifenacin. Solifenacin succinate, CAS No. 242478-38-2, chemical name 1-azabicyclo[2.2.2]octan-8-yl-(1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate succinate, is prepared by condensing (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline (I) with triphosgene under organic base (weak base) conditions to obtain (S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carbonyl chloride (II). Compound II can be directly heated in the presence of an organic base without separation through a one-pot method, and condensed with (R)-3-quinuclidine to obtain solifenacin (III), which is then salified with succinic acid to obtain solifenacin succinate (IV).


Brand: Soarwin

CAS No.: 118864-75-8

EC Number:1806241-263-5

Molecular Formula: C15H15N

Density: 1.065 

Melting point:80-82°C

Boiling point: 338°C

Flash point:167°C


Company Profile Introduction

Chongqing Soarwin Technology Co., Ltd is located in Chongqing. It is an enterprise dedicated to the research, development, production, and sales of chemical reagents, pharmaceutical intermediates, plant extracts, and chemical raw materials. It is a pharmaceutical company guided by the global pharmaceutical market demand and integrates innovative drug research and development, industrialization, and market operation. At present, the company has submitted 10 domestic patents and 1 PCT patent (international patent); and obtained 7 invention patents. The company has strong technical strength, advanced equipment, a strict quality management system, and high-quality after-sales service.

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  • Since: 2025-02-19
  • Address: 10-11, Building 4, No. 18 Jinshan Road, Longxi Street, Yubei District, Chongqing, China
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