
(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline NEW
Price | Get Latest Price | ||
Package | 1kg | 10kg | 50kg |
Min. Order: | 1kg |
Supply Ability: | 20 tons |
Update Time: | 2025-05-28 |
Product Details
Product Name: (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline | CAS No.: 118864-75-8 |
EC-No.: 1806241-263-5 | Min. Order: 1kg |
Purity: 99.99% | Supply Ability: 20 tons |
Release date: 2025/05/28 |
(S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline can be used to prepare solifenacin. Solifenacin succinate, CAS No. 242478-38-2, chemical name 1-azabicyclo[2.2.2]octan-8-yl-(1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate succinate, is prepared by condensing (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline (I) with triphosgene under organic base (weak base) conditions to obtain (S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carbonyl chloride (II). Compound II can be directly heated in the presence of an organic base without separation through a one-pot method, and condensed with (R)-3-quinuclidine to obtain solifenacin (III), which is then salified with succinic acid to obtain solifenacin succinate (IV).
Brand: Soarwin
CAS No.: 118864-75-8
EC Number:1806241-263-5
Molecular Formula: C15H15N
Density: 1.065
Melting point:80-82°C
Boiling point: 338°C
Flash point:167°C
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- Since: 2025-02-19
- Address: 10-11, Building 4, No. 18 Jinshan Road, Longxi Street, Yubei District, Chongqing, China
+86-15790943001
crystal@sorawin.cn