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Postion:Product Catalog >API>Nervous system drugs>Antidepressants, Antimanics drugs>Amitriptyline Hydrochloride
Amitriptyline Hydrochloride
  • Amitriptyline Hydrochloride
  • Amitriptyline Hydrochloride
  • Amitriptyline Hydrochloride
  • Amitriptyline Hydrochloride
  • Amitriptyline Hydrochloride

Amitriptyline Hydrochloride

Price $1000
Package 1KG
Min. Order: 50g
Supply Ability: 2000tons
Update Time: 2024-02-22

Product Details

Product Name: Amitriptyline Hydrochloride CAS No.: 549-18-8
EC-No.: 208-964-6 Min. Order: 50g
Purity: 99% Supply Ability: 2000tons
Release date: 2024/02/22


99% Amitriptyline Hydrochloride/Amitriptyline HCl 549-18-8 For Antidepressants


Quick  Details 


Name: Amitriptyline hydrochloride
Synonyms: Amitriptyline hydrochloride; amitriptyline hcl methanol solution; AMITRYPTILLINE HCL; Amitriptyline HCl
CAS Registry number: 549-18-8
EINECS:208-964-6
Molecular Formula: C20H23NHCl
Boiling Point: 398.2 °C at 760 mmHg
Flash Point: 174 °C
Density: 1.076g/cm3
Water:slightly soluble in Water
Appearance: white to off-white powder
Usage:Antidepressant.
Safety Statements: S22;S26;S36/37/39;S45
Transport:UN 2811

 

Basic Information


 

Product Name:Amitriptyline hydrochloride
Synonyms:3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride;Amiplin;Normaln;Amitriptyline Hydrochloride (200 mg);Methanol (test Amitriptyline HCl, 1.0 mg/mL as free base);Amitriptyline hydrochloride 98+%;Amitriptyline hydrochloride solution ;3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
CAS:549-18-8
MF:C20H24ClN
MW:313.86
EINECS:208-964-6


COA:


Items

Specification

Results

Identification

A. Infrared absorption spectrophotometry

Conforms

B.As obtained in the Assay

Conforms

C. Chloride reaction

Conforms

Inspect

Melting point

195~199

195 to 199

196.5~198.0

Acidity

pH is 5.0 to6.0

5.6

Loss on drying

Not more than 0.5 per cent

0.4

Residue on ignition

Not more than 0.1 per cent

0.09

Heavy metals

Not more than 0.001

0.001

Related substances

 

Conforms

Conforms

Content

98.0 per cent to 102.0 per cent

99.4


Usage:


Amitriptyline Hydrochloride is an antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.

 

Amitriptyline is used in ankylosing spondylitis for pain relief as a preventive for patients with frequent/chronic migraines. It is also used as a preventive for patients with recurring biliary dyskinesia (sphincter of Oddi dysfunction) Amitriptyline is also used in the treatment of nocturnal enuresis in children.

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