AZD3759
| Price | $50 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 20ton |
| Update Time: | 2021-08-07 |
Product Details
| Product Name: AZD3759 | CAS No.: 1626387-80-1 |
| Min. Order: 1KG | Purity: 99 |
| Supply Ability: 20ton | Release date: 2021/08/07 |
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| Product Name: | AZD 3759 |
| Synonyms: | AZD 3759;AZD3759;AZD-3759;(2R)-2,4-Dimethyl-1-piperazinecarboxylic acid 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester;HY-18750;azd3579;1-Piperazinecarboxylic acid, 2,4-dimethyl-, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester, (2R)-;1-PIPERAZINECARBOXYLIC ACID, 2,4-DIMETHYL-, 4-[(3-CHLORO-2-FLUOROPHENYL)AMINO]-7-METHOXY-6-QUINAZOLINYL ESTER |
| CAS: | 1626387-80-1 |
| MF: | C22H23ClFN5O3 |
| MW: | 459.9 |
| EINECS: | 1592732-453-0 |
| Product Categories: | API |
| Mol File: | 1626387-80-1.mol |
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AZD3759 is a selective EGFR inhibitor that can fully penetrate the blood-brain barrier (BBB), with equal free concentrations in the blood, cerebrospinal fluid, and brain tissue. Treatment with AZD3759 causes tumor regression in subcutaneous xenograft, leptomeningeal metastasis (LM), and brain metastasis (BM) lung cancer models and prevents the development of BM in nude mice.
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