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Postion:Product Catalog >API>Antineoplastic agents>Alkylating antineoplastic>Carmustine
Carmustine
  • Carmustine
  • Carmustine
  • Carmustine
  • Carmustine
  • Carmustine

Carmustine NEW

Price Get Latest Price
Package 25KG
Min. Order: 2KG
Supply Ability: 20tons
Update Time: 2024-12-24

Product Details

Product Name: Carmustine CAS No.: 154-93-8
Min. Order: 2KG Purity: 96%-102%
Supply Ability: 20tons Release date: 2024/12/24

Product Information

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COA of Carmustin

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Usage

Function of Carmustine
Carmustine is a nitrosourea alkylating agent. Although it has a chloroethyl group in its structure, its chemical reaction is different from that of nitrogen mustard. Because it can penetrate the blood-brain barrier, it is often used for brain tumors and intracranial metastases.


It is now believed that this product forms isocyanate and diazonium hydroxide through the action of OH- ions under physiological conditions after entering the body. Isocyanates carbamylate proteins, and diazonium hydroxide generates carbanion ions to alkylate biological macromolecules. Isocyanate can inhibit DNA polymerase, inhibit DNA repair and RNA synthesis. This product is a periodic non-specific drug, and it is not completely cross-resistant with general alkylating agents. The resistance of nitrite drugs has little to do with multi-drug resistance genes. This product has high fat solubility. Permeable to the blood-brain barrier, the concentration in cerebrospinal fluid is 50% to 70% of the plasma concentration. It is mainly metabolized in the liver. The metabolites stay in the plasma for several days and still have anticancer effects. They are slowly released after binding to the protein and have a lasting effect.


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Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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  • Since: 1996-07-16
  • Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.
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