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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antiviral drugs>Emtricitabine
Emtricitabine
  • Emtricitabine
  • Emtricitabine
  • Emtricitabine
  • Emtricitabine
  • Emtricitabine

Emtricitabine

Price Get Latest Price
Package 25KG
Min. Order: 2KG
Supply Ability: 20 tons
Update Time: 2024-12-20

Product Details

Product Name: Emtricitabine CAS No.: 143491-57-0
EC-No.: 604-363-1 Min. Order: 2KG
Purity: 99% up, DMF, FDA (zero defect) Supply Ability: 20 tons
Release date: 2024/12/20

Product Information

Product name

Emtricitabine

CAS No.

143491-57-0

Molecular Formula

C8H10FN3O3S

Molecular Weight

247.247

Quality Standard

98% up, Medicine Grade

Appearance

White powder

COA of Nonapeptide-1

TEST

SPECIFICATION

RESULTS

Appearance

White to off-white powder

White powder

Identification

By chiral HPLC: the retention time of the main peak corresponds within 2.0% to that of the cis-(-)-EMTB reference standard

< 0.1%

Conforms


By IR: Consistent with the reference standard

Conforms 

Clarity of solution (1% w/v in water)

  Clear, essentially free of visible particles

Conforms

Water Content

NMT 0.5%

< 0.1%

Heavy Metals as lead

NMT 20 ppm

< 10 ppm

Residue on ignition

NMT 0.2%

0.1%

Bulk density

Report data

0.20 g/mL

Particle size by laser light scattering

d50  30

24

d90: 45~75

51

Residual solvent

Methanol  0.20%

ND

Isopropyl acetate  0.20%

ND

l-propanol  1.00%

0.05

Any unspecified solvent  0.10 or  the premitted daily exposure specified by ICH Q3C

ND

EMTB-Dioxolane

 0.70%

ND

EMTB-Carboxylic acid

 0.50%

ND

EMTB-Disulfide

 0.30%

ND

Emtb sulfoxides

 0.15%

0.05%

Any unspecified impurity by HPLC

 0.10%

Trace

Total impurities by

 1.0%

0.1%

Assay by HPLC

98.0~102.0 (Dried basis)

100.1

98.0~102.0 (Anhydrous basis)

100.1

Drug content factor(Report data)

0.999

cis-(-)chiral purity by HPLC(%)

cis-(-)-EMTB  98.5

100.0

cis-(+)-EMTB (report data)

Trace

trans-(-)-EMTB (report data)

ND

trans-(+)-EMTB (report data)

ND

CONCLUSION

LOT MEETS SPECIFICATION

Usage

Function of Emtricitabine


Emtricitabine is a new type of nucleoside reverse transcriptase inhibitor that has antiviral activity against HIV-1, HIV-2 and HBV. This product is phosphorylated into cellular active 5'-triphosphate after oral administration. The 5'-triphosphate enters the viral DNA backbone and binds to the backbone, resulting in chain termination, thereby inhibiting HIV-1 reverse transcriptase and HBV DNA polymerase activity.


Emtricitabine does not affect the liver microsomal enzyme P450 enzyme system, and does not produce drug interactions mediated by it. It is used in combination with tenofovirindinavirfamciclovir, and stanvudine, with almost no pharmacokinetics influences.

Our advantages of Emtricitabine (CAS: 143491-57-0)  :
1. Quality: 99% up, full test report. 

2. Documents: DMF, our facotory pass FDA audit with Zero defect. passing MCC in South African,
3. Large capacity & stock :80MT per year with 1000kg in stock for prompt shipment
4. Better payment terms : We can make use of Export Credit Insurance after confirming yr credit report accepted by Sinosure.

5. Various shipping ways for your choice : by air./ by sea / by courier (DHL/FedEx).

6. we also provide TDF, TAF, Efavirenz, that used togher with Emtritabine as the Compound Preparation to treat HIV.

 

The main Compound Preparation:

TDF+Emtricitabine and TDF+Emtricitabine+Efavirenz.


Other anti-virus products.

 

1. Oseltamivir phosphate 99%

2. Tenofivir Disoproxil Fumarate 99% 

3. Lamivudine USP

4. Zidovudine USP
5. Lopinavir  USP

6. Ritonavir USP

7. Remdesivir USP

8. Abacavir sulfate USP

9. Efavirenz

10. TAF


Article illustration



Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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