1,3,6-Tri-O-galloyl-beta-D-glucose NEW
Price | $118 | $291 | $432 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: 1,3,6-Tri-O-galloyl-beta-D-glucose | CAS No.: 18483-17-5 |
Purity: 99.37% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | 1,3,6-Tri-O-galloyl-beta-D-glucose |
Description | 1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) is a phenolic compound found in Black Walnut Kernels, exhibiting anti-inflammatory activity. |
In vitro | The compounds were isolated by silica gel column chromatography, Sephadex LH-20 column chromatography and ODS column chromatography.Their structures were elucidated by spectral analyses and physicochemical properties. The anti-inflammatory activities of selected isolated compounds were evaluated as inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cell lines by Griess reaction. Eight compounds were obtained from n-butanol fraction oi Mangifera indica L. seed kernel, whose structures were elucidated as 4-O-ethylgallic acid (1), gallic acid (2), citric acid(3), 1,2,3,4,6-penta-O-galloylglucose(4),1,3,6-Tri-O-galloylglucose(5), hyperoside(6), quercetin-3-O-rhamnopyranoside(7), and mangiferin(8). Compounds 1, 2 and 4-8 exhibited potent inhibitory effect on NO production in LPS-induced macrophages, especially compounds 6 and 8 showed the best inhibitory activity with IC50 values of 16.5 and 19.5 μmol·L-1, respectively. |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | inhibit | Inhibitor | 1,3,6-Tri-O-galloyl-b-D-glucose | 1,3,6-Tri-O-galloyl-beta-D-glucose | 1,3,6TriOgalloylbetaDglucose | 1,3,6 Tri O galloyl beta D glucose |
Inhibitors Related | ZLDI-8 | Glimepiride sulfonamide | Fenclozic acid | beta-Escin | 8-Epideoxyloganic acid | Anti-inflammatory agent 36 | Bucolome | Anti-inflammatory agent 35 | Fendosal | Ataquimas | Anti-inflammatory agent 34 | TL4-12 |
Related Compound Libraries | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Tibetan medicine Compound Library | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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