Description of Rifaximin from Wuhan Fortuna Chemical Co.,Ltd

Specifications(COA) of Manufacturer supply Rifaximin Powder CAS 80621-81-4 Antibiotics with good quality

Introduction of Rifaximin.

Rifaximin is a broad-spectrum antibiotic that is primarily used to treat gastrointestinal conditions.   It is a semi-synthetic derivative of rifamycin, an antibiotic that is effective against a wide range of bacteria.   Rifaximin works by inhibiting bacterial RNA synthesis, thereby preventing the bacteria from growing and reproducing.

Here are some key points about Rifaximin:

Mechanism of Action: Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting the synthesis of RNA and leading to the death of the bacteria.

Spectrum of Activity: It is effective against a variety of Gram-positive and Gram-negative bacteria, but its activity is mostly confined to the gastrointestinal tract because it is poorly absorbed into the bloodstream.

Application of Rifaximin.

Rifaximin is used primarily for the treatment of various gastrointestinal conditions. Here are the main applications of Rifaximin:

Traveler’s Diarrhea: Rifaximin is used to treat traveler’s diarrhea caused by non-invasive strains of Escherichia coli. It helps reduce the duration and severity of diarrhea in travelers.

Irritable Bowel Syndrome with Diarrhea (IBS-D): Rifaximin is approved for the treatment of IBS-D. It helps alleviate symptoms such as abdominal pain, bloating, and diarrhea by altering the gut microbiota.

Hepatic Encephalopathy: Rifaximin is used to reduce the risk of recurrent episodes of hepatic encephalopathy in patients with liver disease. It works by decreasing the number of ammonia-producing bacteria in the gut, which helps lower blood ammonia levels and reduce the risk of encephalopathy.

Small Intestinal Bacterial Overgrowth (SIBO): Although not officially approved for this indication, Rifaximin is often used off-label to treat SIBO. It helps reduce the overgrowth of bacteria in the small intestine, which can alleviate symptoms such as bloating, gas, and diarrhea.

Clostridium difficile Infection (CDI): Rifaximin may be used as part of a treatment regimen for recurrent CDI, often in combination with other antibiotics like vancomycin or metronidazole. It helps to reduce the bacterial load and prevent recurrence.

Diverticular Disease: Rifaximin is sometimes used off-label to manage symptoms of diverticular disease, such as abdominal pain and bloating, by reducing bacterial overgrowth and inflammation.

Inflammatory Bowel Disease (IBD): In some cases, Rifaximin is used off-label as an adjunct therapy for Crohn’s disease or ulcerative colitis to help manage symptoms and reduce bacterial load.

Other Gastrointestinal Infections: Rifaximin may be used to treat other gastrointestinal infections caused by susceptible bacteria, although this is less common.

Rifaximin’s primary advantage is its poor systemic absorption, which allows it to act locally in the gastrointestinal tract with minimal systemic side effects. This makes it particularly useful for conditions where altering the gut microbiota or reducing bacterial load in the intestines is beneficial.

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is  the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.

Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Rifaximin with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Rifaximin.