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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>Polymyxin B sulfate
Polymyxin B sulfate
  • Polymyxin B sulfate

Polymyxin B sulfate

Price $4062
Package 1KG
Min. Order: 10g
Supply Ability: 1000KG
Update Time: 2021-11-02

Product Details

Product Name: Polymyxin B sulfate CAS No.: 1405-20-5
Min. Order: 10g Purity: 99%
Supply Ability: 1000KG Release date: 2021/11/02
Melting point 217-220°C (dec.)
storage temp. 2-8°C
solubility H2O: 50 mg/mL
form powder
pkapKa 8.9 (Uncertain)
color colorless or slightly yellow
PHpH (10g/L, 25℃) : 4.5~7.0
optical activity[α]/D 20/D (Rotation: -2.3 +/- 0.2 degrees)
Water Solubility Soluble in water at 50mg/ml/n
Merck 14,7573
CAS DataBase Reference1405-20-5(CAS DataBase Reference)
EPA Substance Registry SystemPolymixin B sulfate (1405-20-5)
UsesBiochemical studies. 
Polymyxin B is a kind of anti-Gram-negative poly-peptide antibiotics which can alter membrane structure allowing small molecules leakage and inhibit the growth of Gram-negative bacteria. It has bactericidal effect on Escherichia coli through binding to the lipid A portion of bacterial lipopolysaccharide. Mechanism of action: bind and interfere with the permeability o the cellular membrane. Anti-bacteria spectrum: gram negative bacteria.
Chemical PropertiesWhite Solid
Usesantibacterial
UsesAntibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mixtu re of Polymyxin B1 and B2 sulfate. Biological potency (dry basis): >6000U/mg.
UsesPolymyxin B sulfate is used as topical antibiotic agent, often used in combination with neomycin; products include ointments, creams, eye, and ear drops.


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  • Since: 2018-09-06
  • Address: Room B801, Financial Plaza, Jintai District, Baoji, Shaanxi, CN
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