1,3-Dicaffeoylquinic acid NEW
| Price | $140 |
| Package | 20mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: 1,3-Dicaffeoylquinic acid | CAS No.: 19870-46-3 |
| Purity: 98.68% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | 1,3-Dicaffeoylquinic acid |
| Description | 1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent. |
| Animal Research | The neuroprotective effects of 1,5-DQA against amyloid β(1-42) (Aβ(42))-induced neurotoxicity in primary neuronal culture. To evaluate the neuroprotective effects of 1,5-DQA, primary cultured cortical neurons from neonate rats were pretreated with 1,5-DQA for 2 hours and then treated with 40 μmol/L Aβ(42) for 6 hours. Cell counting kit-8, Hoechst staining and Western blotting were used for detecting the protective mechanism. Comparisons between two groups were evaluated by independent t test, and multiple comparisons were analyzed by one-way analysis of variance (ANOVA). |
| In vivo | CYNARIN have neuroprotective effects.CYNARIN prevents Aβ(42)-induced neurotoxicity through the activation of PI3K/Akt followed by the stimulation of Trk A, then the inhibition of GSK3β as well as the modulation of Bcl-2/Bax. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 23 mg/mL (44.53 mM) |
| Keywords | Phosphoinositide 3-kinase | 1,3 Dicaffeoylquinic acid | PI3K | Akt | inhibit | Protein kinase B | Inhibitor | 1,3Dicaffeoylquinic acid | PKB | 1,3-Dicaffeoylquinic acid | Reactive Oxygen Species |
| Inhibitors Related | Sodium Thiocyanate | Imeglimin hydrochloride | Myricetin | L-Ascorbic acid | α-Vitamin E | Glucosamine | D-(+)-Glucono-1,5-lactone | Artemisinin | Lycopene | Coenzyme Q10 | Naringenin | 2,3-Butanediol |
| Related Compound Libraries | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Kinase Inhibitor Library | Natural Product Library | Miao medicine Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Neuroprotective Compound Library | Natural Product Library for HTS | Ancient Chinese Classical Formulas Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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