1,2-Bis(2-iodoethoxy)ethane NEW
| Price | $29 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: 1,2-Bis(2-iodoethoxy)ethane | CAS No.: 36839-55-1 |
| Purity: ≥98% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | 1,2-Bis(2-iodoethoxy)ethane |
| Description | 1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker used in the synthesis of MT802 and SJF620, which are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, respectively [1]. |
| In vitro | 1,2-Bis(2-iodoethoxy)ethane, a PROTAC linker of the polyethylene glycol (PEG) class, is essential for synthesizing various PROTACs like MT802 and SJF620. Notably, PROTAC MT802 includes a ligand targeting BTK and another targeting the E3 ligase cereblon (CRBN), both bridged by the PEG linker 1,2-Bis(2-iodoethoxy)ethane[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | inhibit | 1,2-Bis(2-iodoethoxy)ethane | Inhibitor | PROTAC Linkers | 1,2 Bis(2 iodoethoxy)ethane | 1,2Bis(2iodoethoxy)ethane |
| Inhibitors Related | Diethylene glycol bis(p-toluenesulfonate) | 6-Maleimidocapronic acid | 11-Aminoundecanoic acid | 1,3-Dibromo-5,5-dimethylhydantoin |
| Related Compound Libraries | NO PAINS Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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