Chemical Name: Tranexamic acid

CAS No.: 701-54-2

Molecular Formula: C8H15NO2

Molecular weight:157.21

Appearance:White or almost white, crystalline powder

Assay: ≥99.0%   

Tranexamic acid typical Properties

 Tranexamic acid for aminomethylbenzoic acid derivatives, is a kind of fibrinolytic hemostatic drug resistance, hemostatic mechanism with the same amino caproic acid, aminomethylbenzoic acid, but the effect is stronger,the intensity of 7 ~ 10 times that of amino caproic acid, aminomethylbenzoic acid 2 times, and similar toxicity. Tranexamic acid structure similar to the lysine, can be competitive inhibitory fibrinolytic enzyme on the fibrous protein adsorption, prevent its activation, protect the fibrin degradation by fibrinolytic enzyme and dissolved, ultimately achieve hemostatic effect. Limitations are suitable for the treatment of acute or chronic, or systemic primary fibrinolysis hyperfunction caused by all kinds of bleeding, such as the obstetric hemorrhage, renal hemorrhage, prostatic hypertrophy, hemorrhage, hemophilia, tuberculosis, coughing up blood, stomach bleeding, liver, lung, spleen and other visceral bleeding after the operation, etc; When the operation can also be used for abnormal bleeding and so on.

Tranexamic acid on insect bites disease clinically, simple purpura, chronic urticaria, eczema, dermatitis, artificial sex urticaria rash, poisoning, and drug eruption etc effect is remarkable, of erythroderma, scleroderma, SLE, multiform erythema, herpes zoster, and alopecia areata also have certain curative effect, the hereditary angioedema curative effect is better. Treatment of chloasma drugs about 3 weeks, 5 weeks pay off, 60 d one period of treatment.

Fuction:

1.Menstrual bleeding

Tranexamic acid exerts its antifibrinolytic effect through the reversible blockade of lysine-binding sites on plasminogen molecules.Tranexamic acid inhibits endometrial plasminogen activator and thus prevents fibrinolysis and the breakdown of blood clots.

Tranexamic acid is used as firstline nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids. The histological appearance of the necrosis in women treated by tranexamic acid is no different from the spontaneous incidence of thrombosis.

2.Orthopedic Surgery

Tranexamic acid is used in orthopedic surgery to reduce bloodloss. Tranexamic acid is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced. Tranexamic acid is commonly used in joint replacement surgery.

3.Trauma

Tranexamic acid should be considered for use in bleeding trauma patients.

Application:

1.Menstrual bleeding of Pure Tranexamic Acid
2.Orthopedic Surgery of Pure Tranexamic Acid
3.Trauma of Pure Tranexamic Acid
4.Dentistry of Pure Tranexamic Acid
5.In obstetrics, tranexamic acid is used after delivery to reduce bleeding, often with 
6.In cardiac surgery, e.g. coronary artery bypass surgery, it is used to prevent excessive blood loss.
7.Whitening effect.Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%