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Postion:Product Catalog >Chemical Reagents>Organic reagents>Phenols>PBP
PBP
  • PBP
  • PBP
  • PBP
  • PBP
  • PBP

PBP

Price $8
Package 1KG
Min. Order: 1KG
Supply Ability: 20 Tons
Update Time: 2020-11-16

Product Details

Product Name: PBP CAS No.: 103-16-2
EC-No.: 203-083-3 Min. Order: 1KG
Purity: 99% Supply Ability: 20 Tons
Release date: 2020/11/16
 
PBP Basic information
Abstract Treatment for vitiligo How to use Category Toxic grading Acute toxicity Stimulate data Flammability hazard characteristics Storage Extinguishing agent References
Product Name: PBP
Synonyms: MONOBENZONE;PBP;P-BENZYLOXYPHENOL;P-HYDROXYPHENYL BENZYL ETHER;HYDROQUINONE MONOBENZYL ETHER;Benzyl hydroquinone;BENZYL P-HYDROXYPHENYL ETHER;4-BENZYLOXYPHENOL
CAS: 103-16-2
MF: C13H12O2
MW: 200.23318
EINECS: 203-083-3
Product Categories: API intermediates;Bifunctional Compounds (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials;treat Vitiligo;whiten agent;cosmetics;B;Bioactive Small Molecules;Building Blocks;C9 to C20+;Cell Biology;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols;API;SANODIN
Mol File: 103-16-2.mol
Article illustration
 
PBP Chemical Properties
Melting point  119-120 °C(lit.)
Boiling point  297.96°C (rough estimate)
density  1,26 g/cm3
refractive index  1.5906 (estimate)
storage temp.  -20°C
form  Powder, Crystals, and/or Chunks
color  Off-white to beige to brown
Water Solubility  slightly soluble
Merck  14,6248
BRN  1958305
InChIKey VYQNWZOUAUKGHI-UHFFFAOYSA-N
CAS DataBase Reference 103-16-2(CAS DataBase Reference)
NIST Chemistry Reference Monobenzone(103-16-2)
EPA Substance Registry System Phenol, 4-(phenylmethoxy)-(103-16-2)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36-43
Safety Statements  24/25-26-37
WGK Germany  2
RTECS  SJ7700000
Hazard Note  Irritant
TSCA  Yes
HS Code  29095090
Hazardous Substances Data 103-16-2(Hazardous Substances Data)
Toxicity LD50 i.p. in mice: >600 mg/kg (Takahashi)
PBP Usage And Synthesis
Abstract Monobenzone, also called 4-(Benzyloxy)phenol and monobenzyl ether of hydroquinone (MBEH) is an organic chemical in the phenol family with chemical formula C6H5CH2OC6H4OH. It is used as a topical drug for medical depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water.
The topical application of monobenzone in animals, increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans.
Treatment for vitiligo Monobenzone may cause destruction of melanocytes and permanent depigmentation.Hyperpigmented skin appears to fade more rapidly than does normal skin, and exposure to sunlight reduces the depigmenting effect of the drug. The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes.This function enables it treat the uneven appearance of the skin due to a loss of skin color (vitiligo). It works by permanently removing color from normal skin located around skin with vitiligo. This will help to make the appearance of the skin more even.  
What calls for special attention is that: Do not use this drug to treat other skin discoloration problems ("sun spots," "age spots," freckles, skin discoloration caused by hormone medicine, perfumes, pregnancy, or skin trauma). Monobenzone is not a mild cosmetic bleach. Because it causes a permanent discoloration of the skin, it may not be the right treatment for these other skin conditions.
Besides, Monobenzone is also being considered for the treatment of Melanoma.
How to use This medication is for use on the skin only. Apply a thin layer of the medication to normal-colored skin, usually 2-3 times daily or as directed by your doctor. Avoid getting this product in your eyes or on the inside of your nose or mouth. If you do get this medication in those areas, flush with plenty of water.After using this medication, the skin will be permanently affected and sensitive to sunlight. Avoid prolonged exposure to sunlight, tanning booths, and sunlamps. Always use a sunscreen of SPF 15 or greater, and wear protective clothing when outdoors.It may take up to 4 months before the full benefit of this drug takes effect. Once the desired skin color is achieved, this medication is applied only as needed to maintain your new skin color (usually 2 times a week).Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.Inform your doctor if your condition persists or worsens after 4 months.
You should not use this medication if you are allergic to monobenzone. Do not use monobenzone on any areas that are not affected by vitiligo.
Category Toxic substance
Toxic grading Moderate toxicity
Acute toxicity Abdomen-rat LD50: 4500 mg/kg
Stimulate data Skin-guinea pigs 5%/48 hours,  mild grade.
Flammability hazard characteristics The drug is combustible, and combustion releases stimulus smoke.
Storage Ventilated warehouse, low temperature, dry; Separated from food raw materials.
Extinguishing agent Dry powder, foam, sand, carbon dioxide, mist water.

Company Profile Introduction

Longyan Tianhua Biological Technology Co., Ltd is located in Longyan city, Fujian Province, China. It is a large-scale high-tech integrated enterprise dedicated to the research, development and sales of fine chemicals, pharmaceutical raw material intermediates, food and feed additives. The company has its own research and development base, equipped with advanced production equipment and efficient and precise testing instruments, has set up a strict and scientific quality management system, and constantly committed to technological innovation, product innovation and management innovation, so as to ensure that our products have super competitiveness in the same industry.? Company's main: Phenformin Hydrochloride, Chlorhexidine Acetate, Indomethacin Biphenyl benzyl azole dyclonine hydrochloride clorprenaline hydrochloride griseofulvin chloramphenicol maleic acid to guangxi pp qi, fucus xanthine tert-butyl of hydroxy anisole (BHA), ammonia, benzene pteridine zonisamide moxifloxacin mother nucleus moxifloxacin side chain moxifloxacin hydrochloride clobetasol propionate tranexamic acid raw material, and so on.? The annual sales volume of the company is around 3 million DOLLARS. Its products have been sold to more than 40 countries and regions all over the world, and have been well received. Moreover, the buyback rate of customers is very high. Longyan Tianhua Biotechnology Co., LTD. Is looking forward to long-term cooperation with you.

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