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Postion:Product Catalog >Biochemical Engineering>Condensing agent>N-Hydroxy succinimide
N-Hydroxy succinimide
  • N-Hydroxy succinimide
  • N-Hydroxy succinimide
  • N-Hydroxy succinimide
  • N-Hydroxy succinimide
  • N-Hydroxy succinimide

N-Hydroxy succinimide NEW

Price $40
Package 1KG
Min. Order: 1KG
Supply Ability: 30tons/month
Update Time: 2024-10-25

Product Details

Product Name: N-Hydroxy succinimide CAS No.: 6066-82-6
EC-No.: 228-001-3 Min. Order: 1KG
Purity: 99%min Supply Ability: 30tons/month
Release date: 2024/10/25

N-Hydroxy succinimide

Product name : N-Hydroxy succinimide
Molecular formula :

C4H5NO3

Chemical structure : Article illustration
CAS NO. : 6066-82-6
Appearance : white or off-white crystal
Content : 99% min
Use : Drug, pesticide etc.
Packing : 25kg cardboard drum

 

N-hydroxysuccinimide, NHS, is an organic compound with the formula C4H5NO3, which is slightly acidic and irritating to skin, eyes, and mucosa.

Production method:

1. Heat 100g(1.0mol) succinic anhydride and 70g(1.0mol) hydroxylamine hydrochloride together to make the reaction system maintain negative pressure to remove the volatiles generated, rapidly heat to above 125 ° C, and slowly rise to 160 ° C after 1h.Stop heating. When the temperature drops to 125℃, pour the liquid reactants into 400ml of ether and stir vigorously.After the product is cured, the ether layer is dumped, the cured product is coheated to boiling with 400mL butanol, and the filtrate is quickly cooled to 0℃.After 1h of filtration, the crystals were washed successively with butanol and ethyl ether. The crude products were recrystallized with ethyl acetate, and 50g finished products were obtained with a yield of 44%.

 

Application:

N-hydroxysuccinimide and its derivatives are important raw materials for the synthesis of peptides, antibiotics, amino acids and proteins.N-hydroxysuccinimide is used to prepare active ester, inhibit the occurrence of external optical rotation when the peptide is coupled, etc. It has a very wide range of USES in medicine, and is the basic chemical raw material.Used for synthesis of amino acid protectants, semi - synthesis of kanamycin and pharmaceutical intermediates.


Company Profile Introduction

Hebei Yanxi Chemical Co. LTD., mainly produce the Carbomer940/980/u21 and lead acetate and lead oxide, lead stearate, lead salt, at the same time operating organic intermediates, surfactants, Food additive,inorganic salt, plant extracts, cosmetics raw material, etc., through long-term development, hebei said bush chemical co., LTD. In hebei province has become a collection of r &d, production, sales in the integration of high-tech enterprises.

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  • Since: 2020-05-25
  • Address: Zhanggeji Village, Fengjiazhai Town, Guangzong County, Xingtai City, Hebei Province
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