α-Zearalenol NEW
| Price | $108 | $578 | $825 |
| Package | 1mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: α-Zearalenol | CAS No.: 36455-72-8 |
| Purity: 90% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | α-Zearalenol |
| Description | α-Zearalenol is one of the major metabolites of Zearalenone. α-Zearalenol has structural analogy to estrogen, thus α-Zearalenol can bind to estrogen receptors (ERs). |
| In vitro | α-Zearalenol (0.001-10 μM; 24-72 hours) shows the highest RPE (90.5%) at 9.37 μM α-ZOL exposure in MFC-7 cells (IC50: 12.5 μM) [1].α-Zearalenol (0.001-10 μM; 24-72 hours) induces an increase of cell viability on MCF-7 cells mainly after 72 h of treatment whereas it is slightly cytotoxic on MDA-MB231 cells. It increases the MCF7 cell population in the S phase and in the G2/M phase, no visible change in cell cycle phases is observed in MDA-MB231 cells. α-Zearalenol (1-10 μM; 24 hours) reduces the expression of TNF-α, α-Zearalenol combines with β-ZOL shows an antagonistic effect on inflammation for IL-1β and act synergically for IL-8 at high toxin concentrations [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 60 mg/mL (187.28 mM) |
| Keywords | Inhibitor | Estrogen Receptor/ERR | α Zearalenol | a-Zearalenol | α-Zearalenol | αZearalenol | alpha-Zearalenol | inhibit |
| Inhibitors Related | Kaempferol | Tamoxifen | Estradiol | Estradiol benzoate | ARV-471 | Cholesterol | Estriol | Chrysin | Ethisterone | Estrone |
| Related Compound Libraries | Nuclear Receptor Compound Library | Anti-Ovarian Cancer Compound Library | Endocrinology-Hormone Compound Library | RO5 Drug-like Natural Product Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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