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Postion:Product Catalog >API>Circulatory system drugs>Antiarrhythmics Drugs>(+)-Sparteine
(+)-Sparteine
  • (+)-Sparteine

(+)-Sparteine NEW

Price $42
Package 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: (+)-Sparteine CAS No.: 492-08-0
Purity: 99.90% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Name(+)-Sparteine
Description(+)-Sparteine ??is a quinoline alkaloid extracted from Scotch broom, a sodium channel blocker and a class 1a antiarrhythmic agent. It competitively inhibits the activity of nicotinic acetylcholine receptors in nerve cells and is a ganglionic blocking agent.
In vitro(+)-Sparteine ??(Pachycarpine) (2 μM) reduces ACh-induced currents caused by activation of nicotinic ACh receptors (AChRs) in a voltage-independent manner at membrane potentials between -50 mV and +30 mV; the ACh dose-response relationship is altered by 2 μM (+)-Sparteine ??(Pachycarpine) at -50 mV and -90 mV in a manner typical of a competitive but not competitive antagonist. [1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 5 mg/mL (21.3 mM), Sonication is recommended.
H2O : 2.86 mg/mL (12.20 mM), Sonication is recommended.
KeywordsSparteine | inhibit | Inhibitor | (+) Sparteine | nAChR | (+)-Sparteine | (+)Sparteine | Nicotinic acetylcholine receptors
Inhibitors RelatedAdiphenine hydrochloride | Nanofin | Arecoline hydrobromide | Forskolin | Pilocarpine Hydrochloride | CLOZAPINE N-OXIDE | Pilocarpine nitrate | Ribavirin | Adenine | Amitriptyline hydrochloride | Choline chloride | Propoxur
Related Compound LibrariesPain-Related Compound Library | Traditional Chinese Medicine Monomer Library | Anti-Neurodegenerative Disease Compound Library | Alkaloid Natural Product Library | Membrane Protein-targeted Compound Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Ion Channel Targeted Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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