δ-secretase inhibitor 11 NEW
| Price | $97 | $167 | $249 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-01 |
Product Details
| Product Name: δ-secretase inhibitor 11 | CAS No.: 842964-18-5 |
| Purity: 99.4% | Supply Ability: 10g |
| Release date: 2025/06/01 |
Product Introduction
Bioactivity
| Name | δ-secretase inhibitor 11 |
| Description | δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment. |
| In vitro | The inhibitory effect of δ-secretase inhibitor 11 on AEP activity in vitro was tested and the dose-response relationship revealed that the δ-secretase inhibitor 11 had an IC50 value of 0.15?±?0.09?μM [1]. |
| In vivo | It was found that oral administration of δ-secretase inhibitor 11 (10?mg/kg) significantly suppressed brain AEP activity compared to the vehicle treatment. The concentrations of Aβ1–40 and Aβ1–42 in brain lysates of SAMP8 mice were significantly reduced due to AEP inhibition by δ-secretase inhibitor 11. [1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 2.2 mg/mL (9.99 mM), Sonication is recommended. |
| Keywords | δ-Secretase inhibitor 11 | δ-secretase inhibitor 11 | δsecretase inhibitor 11 | δ secretase inhibitor 11 | β-amyloid peptide | βAmyloid | β Amyloid | Pala cells | oxygen-glucose deprivation | Inhibitor | inhibit | delta-secretase inhibitor 11 | CNS diseases | Caspase | BetaAmyloid | Beta Amyloid | bAmyloid | b Amyloid | asparagine endopeptidase | APP | amyloid-β | Amyloid-β | amyloid precursor protein | Alzheimer's disease | AEP | Abeta |
| Inhibitors Related | Taurodeoxycholic acid | Notoginsenoside R1 | Geniposide | Deferoxamine Mesylate | Tramiprosate | 20(S)-Ginsenoside Rg3 | Dihydroergocristine mesylate | Rutin | Tauroursodeoxycholate sodium | (Iso)-Z-VAD(OMe)-FMK | Tauroursodeoxycholate | Methyl tridecanoate |
| Related Compound Libraries | Bioactive Compound Library | Neuronal Signaling Compound Library | Anti-Alzheimer's Disease Compound Library | Membrane Protein-targeted Compound Library | Protease Inhibitor Library | Pyroptosis Compound Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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