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Postion:Product Catalog >API>Antipyretic analgesics>Nonsteroidal Anti-Inflammatory Drugs (NSAIDS)> Loxoprofen
	Loxoprofen
  • 	Loxoprofen
  • 	Loxoprofen

Loxoprofen NEW

Price $5 $0.1
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-04-16

Product Details

Product Name: Loxoprofen CAS No.: 68767-14-6
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/04/16
Lead time: In stock, ready for shipment Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea Origin: Manufacturer, advantage product
COA, MSDS: Available, contact us for details Name: Tina

 1. Materials information

Names

Nameloxoprofen
SynonymMore Synonyms

 Loxoprofen Biological Activity

DescriptionLoxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid.
Related Catalog
Research Areas >> Inflammation/Immunology
Target

COX-1:6.5 μM (IC50, in human whole blood)

COX-2:13.5 μM (IC50, in human whole blood)

References

[1]. Riendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1201-3.

 Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point417.9±20.0 °C at 760 mmHg
Melting Point108.5 - 111oC
Molecular FormulaC15H18O3
Molecular Weight246.302
Flash Point220.7±18.3 °C
Exact Mass246.125595
PSA54.37000
LogP1.87
Vapour Pressure0.0±1.0 mmHg at 25°C
Index of Refraction1.568

 MSDS

Loxoprofen MSDS(Chinese)

 Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXi
Safety PhrasesS22-S24/25
RIDADRNONH for all modes of transport
WGK Germany3
HS Code2918300090

 Synthetic Route

Previous 1/2 Next
Article illustration

ethyl 2-[4-(1-e...

CAS#:68767-26-0

~%

Article illustration

Loxoprofen

CAS#:68767-14-6

Literature: US4161538 A1, ;
Article illustration

2-BENZYLCYCLOPE...

CAS#:2867-63-2

~%

Article illustration

Loxoprofen

CAS#:68767-14-6

Literature: Synthetic Communications, , vol. 14, # 14 p. 1365 - 1372
Article illustration

2-(4-acetylbenz...

CAS#:96824-28-1

~%

Article illustration

Loxoprofen

CAS#:68767-14-6

Literature: Synthetic Communications, , vol. 14, # 14 p. 1365 - 1372

 Precursor & DownStream

Precursor  4


  • Article illustration CAS#:68767-26-0
    ethyl 2-[4-(1-e...

  • Article illustration CAS#:2867-63-2
    2-BENZYLCYCLOPE...

  • Article illustration CAS#:43153-03-3
    Benzeneacetic a...

  • Article illustration CAS#:611-10-9
    Ethyl 2-oxocycl...

DownStream  1


  • Article illustration CAS#:80382-23-6
    Loxoprofen sodium

 Customs

HS Code2918300090
Summary2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles33

More Articles
Determination of nonsteroidal anti-inflammatory drugs in human tear and plasma samples using ultra-fast liquid chromatography-tandem mass spectrometry.

Jpn. J. Ophthalmol. 59 , 364-71, (2015)

To evaluate a new rapid and sensitive method for analyzing human tears and plasma for nonsteroidal anti-inflammatory drugs (NSAIDs) and investigate the influence of the transfer of NSAIDs in an ocular...

Risk of peptic ulcer bleeding associated with Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs, low-dose aspirin, and antihypertensive drugs: a case-control study.

J. Gastroenterol. Hepatol. 30(2) , 292-8, (2015)

The associations between antithrombotic or antihypertensive drugs and peptic ulcer bleeding (PUB) remain unknown, particularly in Asia, where Helicobacter pylori infection is prevalent. This study aim...

Effect of X-ray exposure on the pharmaceutical quality of drug tablets using X-ray inspection equipment.

Drug Dev. Ind. Pharm. 41 , 953-8, (2015)

X-ray inspection equipment is widely used to detect missing materials and defective goods in opaque containers. Its application has been expanded to the pharmaceutical industry to detect the presence ...

 Synonyms

IOXOPROFEN
MFCD00864331
KOLOXO
Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
2-{4-[(2-Oxocyclopentyl)methyl]phenyl}propanoic acid
Loxoprofen


2. Packaging of materials

  • For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

  • For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                             Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping & Delivery

  • By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

Article illustration


  • By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

Article illustration


  • By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 13213167925

WhatsApp/Skype/Wechat/LINE: 86 13213167925



Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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