(-)-Epigallocatechin Gallate NEW
| Price | $43 | $57 | $138 |
| Package | 50mg | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-29 |
Product Details
| Product Name: (-)-Epigallocatechin Gallate | CAS No.: 989-51-5 |
| Purity: 99.26% | Supply Ability: 10g |
| Release date: 2025/05/29 |
Product Introduction
Bioactivity
| Name | (-)-Epigallocatechin Gallate |
| Description | (-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells. |
| Cell Research | LoVo, SW480, HCT-8, and HT-29 cells are seeded in 96-well plates at a concentration of 5×103?cells; each cell line is totally seeded in the 12 wells. Complete medium is added to the wells, up to 200 μL; the medium contains 0 μg/mL, 10 μg/mL, 20 μg/mL, and 35 μg/mL of epigallocatechol gallate. The inhibition rate=[1 - (absorbance of Epigallocatechol Gallate group - absorbance of control group)/(absorbance of control group - absorbance of blank control group)] × 100. |
| In vitro | METHODS: Human thyroid cancer cells TT, TPC-1 and ARO were treated with (-)-Epigallocatechin Gallate (10-200 μM) for 24 h. Cell viability was detected using MTS assay. |
| In vivo | METHODS: To investigate the protective effect against acute injury, (-)-Epigallocatechin Gallate (200 mg/kg) was administered to ICR mice by gavage once a day for one week, followed by intraperitoneal injection of LPS (15 mg/kg) to induce acute injury. RESULTS: (-)-Epigallocatechin Gallate protects mice from LPS-induced acute stress, while stabilizing gut microorganisms, improving sphingolipid metabolism, and inhibiting harmful metabolite levels. [3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 100 mg/mL (218.16 mM), Sonication is recommended. H2O : 50 mg/mL (109.08 mM), Sonication is recommended. Ethanol : 45.8 mg/mL (99.92 mM), Sonication is recommended. |
| Keywords | Thyroid cancer | ReactiveOxygenSpecies | Reactive Oxygen Species | MitochondrialMetabolism | Mitochondrial Metabolism | LPS-induced bone resorption | Inhibitor | inhibit | HIVProtease | HIV Protease | HIV | Ferroptosis | FB-2 cells | Epigallocatechin Gallate | EndogenousMetabolite | Endogenous Metabolite | colorectal cancer | cell proliferation. | Autophagy | ()Epigallocatechin Gallate | ( ) Epigallocatechin Gallate |
| Inhibitors Related | Sucrose | Emtricitabine | Cysteamine hydrochloride | Hydroxychloroquine | Lamivudine | Daidzein | Ferulic Acid | Paeonol | Glycerol | Thymidine | Alginic acid | 3-Indoleacetic acid |
| Related Compound Libraries | Anti-Cancer Clinical Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Drug Repurposing Compound Library | Antiparasitic Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-infective Natural Product Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Ancient Chinese Classical Formulas Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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