3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine NEW
Price | $10 | $5 | $3 |
Package | 1kg | 25kg | 180kg |
Min. Order: | 1kg |
Supply Ability: | g-kg-tons, free sample is available |
Update Time: | 2024-04-29 |
Product Details
Product Name: 3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | CAS No.: 330786-24-8 |
Min. Order: 1kg | Purity: 99% |
Supply Ability: g-kg-tons, free sample is available | Release date: 2024/04/29 |
Lead time: In stock | Origin: Manufacturer |
Packaging: bottle/drum/bucket/IBC, as request. | Delivery: By sea, by air, by express |
Name: Sun |
1. Product information
Name | 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
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Synonym | More Synonyms |
Description | Ibrutinib deacryloylpiperidine (IBT4A) is an impurity of Ibrutinib[1]. Ibrutinib is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[2]. |
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Related Catalog | Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk |
References | [1]. Somana Siva Prasad, et al. A QUALITY BY DESIGN APPROACH FOR DEVELOPMENT OF SIMPLE AND ROBUST REVERSED PHASE STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF IBRUTINIB AND ITS IMPURITIES. [2]. Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80. |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 577.4±50.0 °C at 760 mmHg |
Molecular Formula | C17H13N5O |
Molecular Weight | 303.318 |
Flash Point | 303.0±30.1 °C |
Exact Mass | 303.112000 |
PSA | 89.71000 |
LogP | 3.01 |
Vapour Pressure | 0.0±1.6 mmHg at 25°C |
Index of Refraction | 1.734 |
Storage condition | 2-8°C |
Hazard Codes | Xi |
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Precursor 2 | |
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DownStream 0 |
3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)- |
3-(4-Phenoxyphenyl)-1H-pyrazolo(3,4d)pyrimidin-4-amine |
5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine |
Ibrutinib Impurity 8 |
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
Email address : sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/: 86 13526505137
Company Profile Introduction
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- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro