Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
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marketing@targetmol.cn |
Products Intro: |
Product Name:BAY 2476568 CAS:2311901-93-4 Package:50mg/RMB 24219;25mg/RMB 18600
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4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]- manufacturers
- BAY 2476568
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- $2890.00 / 50mg
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2024-11-19
- CAS:2311901-93-4
- Min. Order:
- Purity:
- Supply Ability: 10g
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| 4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]- Basic information |
Product Name: | 4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]- | Synonyms: | 4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]-;BAY 2476568 | CAS: | 2311901-93-4 | MF: | C24H27FN4O4 | MW: | 454.49 | EINECS: | | Product Categories: | | Mol File: | 2311901-93-4.mol | ![4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]- Structure](CAS/20210305/GIF/2311901-93-4.gif) |
| 4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]- Chemical Properties |
Boiling point | 663.6±55.0 °C(Predicted) | density | 1.275±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | form | Solid | pka | 13.39±0.20(Predicted) | color | Off-white to light yellow |
| 4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]- Usage And Synthesis |
Biological Activity | BAY 2476568 is a potent and selective EGFR inhibitor, with IC50s of < 0.2 nM for wild-type EGFR and several mutations (EGFRR ex20insSVD, EGFRR ex20insASV, EGFRR ex20insNPG)[1]. | References | [1]. Stephan Siegel, et al. 4h-pyrrolo[3,2-c]pyridin-4-one derivatives. WO2019081486A1. |
| 4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]- Preparation Products And Raw materials |
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